DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tou and ZK1010.10

DIOPT Version :9

Sequence 1:	NP_001097270.1	Gene:	tou / 36241	FlyBaseID:	FBgn0033636	Length:	3131	Species:	Drosophila melanogaster
Sequence 2:	NP_001255185.1	Gene:	ZK1010.10 / 13191684	WormBaseID:	WBGene00164985	Length:	194	Species:	Caenorhabditis elegans

Alignment Length:	225	Identity:	42/225 - (18%)
Similarity:	70/225 - (31%)	Gaps:	68/225 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  2600 HPNTSDSDSDFGKRTKKKSGGKRRRSANNTNSSKYSNSLQNCQFCTSGENEDKLLLCDG------ 2658
            :|..|.....|..|.   |...|....||.....:::|      |......:|:.:.:.
Worm     2 NPALSPDQPFFDNRV---SSSSRIEHINNDGPMSFTSS------CMRDMGREKIEIVERGLLHAL 57

  Fly  2659 -CDKGYHTYCFKPKMDNIPDGDWYCYECVNKATNERKCIVCGGHRPSPVGKMIYCDLCP-----R 2717
             |.:.:|:.|.            .|.......::.|||:    .|...|     |::|.     .
Worm    58 YCPRAHHSCCL------------LCTRMKFVISHTRKCV----RRRREV-----CEVCSTVVSIT 101

  Fly  2718 AYHA------DCYIPPLLKVPRGKWYCHGCISRAPPPKKRSAGGTSGSSSKSRRDRDRESGGSAK 2776
            .:||      :|.||          :||         :.|.|..|..:.|....|.|.......:
Worm   102 VFHARVCDEEECQIP----------FCH---------EIRDAMETYSAGSYHLYDLDHLVHRVVR 147

  Fly  2777 RRSDNSKTPAMEHMQQQQMPLAGGDSHHHH 2806
            |..|.|....:...:..:..:| ||.|.::
Worm   148 RLQDLSPDQQLSDEEDGEAEVA-GDQHWNY 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tou	NP_001097270.1	HAT_MBD	953..1027	CDD:238691
		ZapA	1021..1127	CDD:294720
		MAP7	1043..1198	CDD:283355
		RILP-like	1085..>1179	CDD:304877
		DDT	1255..1317	CDD:280886
		WHIM1	1406..1455	CDD:292246
		WHIM3	2190..2224	CDD:292248
		PHD_BAZ2A_like	2640..2685	CDD:277020	6/51 (12%)
		RanBP2-type Zn finger	2640..2659	CDD:275375	2/25 (8%)
		RanBP2-type Zn finger	2680..2698	CDD:275376	4/17 (24%)
		PHD	2695..2744	CDD:279022	12/59 (20%)
		Bromo_BAZ2A_B_like	3027..3123	CDD:99935
ZK1010.10	NP_001255185.1	zf-TAZ	55..115	CDD:366931	14/80 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900