DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tou and Brdt

DIOPT Version :9

Sequence 1:	NP_001097270.1	Gene:	tou / 36241	FlyBaseID:	FBgn0033636	Length:	3131	Species:	Drosophila melanogaster
Sequence 2:	XP_006534791.1	Gene:	Brdt / 114642	MGIID:	1891374	Length:	961	Species:	Mus musculus

Alignment Length:	264	Identity:	65/264 - (24%)
Similarity:	102/264 - (38%)	Gaps:	67/264 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  2874 EDVPGGANVMPGVYPVYTPVAAGNFSAGLINQAPVQPAMPFA---NVVAMSPRAVTPTRTRTPTP 2935
            :::|.|   :|.:            |...:|.|  |.|.|..   ::|.::........|.|||.
Mouse   174 QEIPSG---LPDI------------SLSPLNMA--QEAPPICDSQSLVQITKGVKRRADTTTPTT 221

  Fly  2936 TPAPTPPPPPPTPLLMQASPTATALHVNACQS---PPQQQHAQLMTMPSPPAIGVGTATNQMSPP 2997
            :.|......|||  |.:..|....:..|..::   ..||||..|.|:         ..|.|:
Mouse   222 SIAKASSESPPT--LRETKPVNMPVKENTVKNVLPDSQQQHKVLKTV---------KVTEQL--- 272

  Fly  2998 PINIHAIQEAKEKLKQEKKEKHATKKLMKELAVCKTLLGEMELHEDSWPFLLPVNTKQ--FPTYR 3060
                                ||.: :::||:...|.|       ..:|||..||:...  ...|.
Mouse   273 --------------------KHCS-EILKEMLAKKHL-------PYAWPFYNPVDADALGLHNYY 309

  Fly  3061 KIIKTPMDLSTIKKKLQDLSYKTREDFCVDVRQIFDNCEMFNEDDSPVGKAGHGMRKFFESRWGE 3125
            .::|.||||.|||.|:.:..||...:|..|||.:|.||..:|..|..|......::..||..:.:
Mouse   310 DVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYNPPDHEVVAMARTLQDVFELHFAK 374

  Fly  3126 LTDK 3129
            :.|:
Mouse   375 IPDE 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tou	NP_001097270.1	HAT_MBD	953..1027	CDD:238691
		ZapA	1021..1127	CDD:294720
		MAP7	1043..1198	CDD:283355
		RILP-like	1085..>1179	CDD:304877
		DDT	1255..1317	CDD:280886
		WHIM1	1406..1455	CDD:292246
		WHIM3	2190..2224	CDD:292248
		PHD_BAZ2A_like	2640..2685	CDD:277020
		RanBP2-type Zn finger	2640..2659	CDD:275375
		RanBP2-type Zn finger	2680..2698	CDD:275376
		PHD	2695..2744	CDD:279022
		Bromo_BAZ2A_B_like	3027..3123	CDD:99935	32/97 (33%)
Brdt	XP_006534791.1	Bromo_Brdt_I_like	26..132	CDD:99929
		Bromo_Brdt_II_like	271..372	CDD:99930	36/131 (27%)
		BET	505..567	CDD:374956
		BRD4_CDT	919..961	CDD:374989
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900