DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment en and RSC58

DIOPT Version :9

Sequence 1:	NP_523700.2	Gene:	en / 36240	FlyBaseID:	FBgn0000577	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_013133.1	Gene:	RSC58 / 850720	SGDID:	S000004023	Length:	502	Species:	Saccharomyces cerevisiae

Alignment Length:	212	Identity:	44/212 - (20%)
Similarity:	76/212 - (35%)	Gaps:	62/212 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 NSSPSSRLGASGSGVNASSPQPQPIPPPSAVSR--------------------DSGMESSDDTRS 407
            |.:|  |||..|:  |.|:.....:||...::|                    :|...|.::..:
Yeast   239 NEAP--RLGFVGA--NTSNIPDPTLPPTEMMTRFLHPNWYALPTTVWLKYGNYNSWAPSFNENGT 299

  Fly   408 ETGSTTTEGGKNEMWPAWV-YCTRYSDRPSSGPRYRRPKQPKDK----TNDEKRPRTAFSSEQLA 467
            ...|||    :..:|...: |...|.         :..|:.|.:    ||:|...|
Yeast   300 VVDSTT----RGLIWLERIGYMDLYE---------KNEKKVKQEELLNTNEEGINR--------- 342

  Fly   468 RLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHT 532
               ::.:||....:.:...:..:.|.|:....|...|     .:||.:|....::|  |.|||.|
Yeast   343 ---KQNDENNKNVDGKSNGVQDDGGDNDNDATIASAN-----SESTENKEQFIIKL--QNLYNWT 397

  Fly   533 TVPLTKEEEELEMRMNG 549
            ..... .::|:|...||
Yeast   398 PSNYI-GDDEIENFRNG 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeobox	457..510	CDD:278475	7/52 (13%)
en	NP_523700.2	Engrail_1_C_sig	512..541	CDD:287495	9/28 (32%)
RSC58	NP_013133.1	Bromodomain	39..122	CDD:413371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24341
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100