Protein Alignment en and hmx3a

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_571709.3
• Gene: hmx3a / 60310
• ZFINID: ZDB-GENE-001020-1
• Length: 297
• Species: Danio rerio
• Alignment Length: 293
• Identity: 79/293 - (26%)
• Similarity: 121/293 - (41%)
• Gaps: 74/293 - (25%)

  Fly   279 PPPMSSKMSDANPEKSAL-GSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNAS------ 336
            |.|:.:      |.|:.| ||.  ::||:|:...|....|     ....|.|.....||
Zfish    32 PKPILA------PTKAGLDGSF--SLSQVGEINFPRFELP-----TQRFALPAYLERASAWWYPY 83

  Fly   337 TISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMES 401
            |:|:::.:..:        .:|..:.:|||:       :|.:..||:......|.|...:...:|
Zfish    84 TLSASAHLHRT--------EAAQKARDSSPT-------TGTDRDSPELVLKSDPDAKDDEDDNKS 133

  Fly   402 SDDTRSETGSTTTEGGKNE----MWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFS 462
            .|:...|  .:.||.||.|    .|       :.||..:.       |:|..|    |:.||.||
Zfish   134 GDEIVLE--ESDTEDGKKEGSIDDW-------KKSDDGAD-------KKPCRK----KKTRTVFS 178

  Fly   463 SEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQG 527
            ..|:.:|:..|:..|||:...|..|::.|.|.|.|:||||||:|.|.|:.      ||.:|.|..
Zfish   179 RSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQ------LAAELEAAN 237

  Fly   528 LYNHTT------VPLTKEEEELEMRMN--GQIP 552
            | :|..      ||:...|.......|  |.:|
Zfish   238 L-SHAAAQRIVRVPILYHENSASESTNTAGNVP 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	25/55 (45%)
		Engrail_1_C_sig	512..542	CDD:431338	9/35 (26%)
hmx3a	NP_571709.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..43		4/16 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..172		23/102 (23%)