Protein Alignment en and CG18599

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 99/531 - (18%)
• Similarity: 159/531 - (29%)
• Gaps: 222/531 - (41%)

  Fly    19 QMQH--LHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAA 81
            ||:|  .|||.||||||||...|    |||...||..      |||
  Fly    74 QMEHQQQHHQLQQQQQQQQHHHH----QQLHTHHQDG------HHP------------------- 109

  Fly    82 HAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDID 146
              |                     ..||.|.....:.|...:.|.||....
  Fly   110 --H---------------------PPTPTTGNNNNNSSSSSNSSSHNSNSN-------------- 137

  Fly   147 VDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQ 211
                            |::|..|..:.|.|.:.::                :|:      |:.|.
  Fly   138 ----------------HREQLAAAAATATSHAQLI----------------EAA------AAHSS 164

  Fly   212 TATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANA 276
            .....:||               .||...:..:|.::.|..|.:    :|:.           |.
  Fly   165 LDVGKSFT---------------IAAILGLQSQRKDYNNAINLS----LHDN-----------NN 199

  Fly   277 VIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISST 341
            :|... ::|...:||                                                :.
  Fly   200 IIGDD-NNKCYTSNP------------------------------------------------NN 215

  Fly   342 SSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAV------SRDSGME 400
            ::...::..|:||.::::.|:|:.....:..:|..::.....|.|.....|.      :..|.::
  Fly   216 NNNNNNNGGSNSGNNNSSPSVNNFNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQ 280

  Fly   401 SSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTN----DEKRPRTAF 461
            |......:                      :..:..:...::|.|...|...    ..||.||.|
  Fly   281 SLQQLHQQ----------------------HHAQQQATLSFQREKLKSDSHKKSALKNKRVRTIF 323

  Fly   462 SSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQ 526
            :.|||..|:.||...:|:....|..|:..|.|.|||:|:||||:|.|.:     |:.|.|.....
  Fly   324 TPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWR-----KHHLELTQQRL 383

  Fly   527 GLYNHTTVPLT 537
            .|...|.:|.|
  Fly   384 ALIRQTQLPGT 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	26/55 (47%)
		Engrail_1_C_sig	512..542	CDD:431338	7/26 (27%)
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	26/60 (43%)