Protein Alignment en and HOXC13

DIOPT Version :9

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_059106.2
• Gene: HOXC13 / 3229
• HGNCID: 5125
• Length: 330
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 71/285 - (24%)
• Similarity: 115/285 - (40%)
• Gaps: 59/285 - (20%)

  Fly   287 SDANPEKS----ALGSLCKAV--------SQIGQPAAP-------TMTQPPLSSSASSLASPPPA 332
            |.|:|.|:    .|||.|.|.        ..:|:|.||       ..|..|...:|...| ||||
Human    47 SGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCA-PPPA 110

  Fly   333 SNASTISSTSSVATSSSSSSSGCSSAASSLN--------------SSPSSRLGASGSGVNAS--- 380
            ...|: |:|.........|..|| ..:.::|              ..||..|........|.
Human   111 PPTSS-SATLGYGYPFGGSYYGC-RLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFA 173

  Fly   381 -----SPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEG----GKNEMWPAWVYCTRYSDRPS 436
                 :...|.:|....||...|:....:.|.: .....||    ..:..|.:.|||::  ::..
Human   174 FYPSFASSYQAMPGYLDVSVVPGISGHPEPRHD-ALIPVEGYQHWALSNGWDSQVYCSK--EQSQ 235

  Fly   437 SGPRYRR------PKQPK-DKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLN 494
            |...::.      |.||: ......::.|..::..||..|::|:..::::|:.:|:::|:...|:
Human   236 SAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLS 300

  Fly   495 EAQIKIWFQNKRAKIKKSTG-SKNP 518
            |.|:.|||||:|.|.||... ||.|
Human   301 ERQVTIWFQNRRVKEKKVVSKSKAP 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeobox	457..510	CDD:278475	18/52 (35%)
		Engrail_1_C_sig	512..541	CDD:287495	3/8 (38%)
HOXC13	NP_059106.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..50		1/2 (50%)
		HoxA13_N	54..166	CDD:315049	27/114 (24%)
		HOX	260..312	CDD:197696	16/51 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I5040
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050