Protein Alignment en and HOXC5

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_061826.1
• Gene: HOXC5 / 3222
• HGNCID: 5127
• Length: 222
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 59/199 - (29%)
• Similarity: 87/199 - (43%)
• Gaps: 24/199 - (12%)

  Fly   325 SLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPP 389
            |:..||||.:.|......:....:......||:||     :|....|...:.........|....
Human    46 SITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAA-----APGHAPGRDEAAPLNPGMYSQKAAR 105

  Fly   390 PSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYR--RPKQPKDKTN 452
            |:...|   .:||.:.:.|...|....|.::              |.:.|:..  ..|.......
Human   106 PALEER---AKSSGEIKEEQAQTGQPAGLSQ--------------PPAPPQIYPWMTKLHMSHET 153

  Fly   453 DEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKN 517
            |.||.||:::..|...|::||:.|||||.|||.::::.|.|||.||||||||:|.|.||.:..|:
Human   154 DGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKS 218

  Fly   518 PLAL 521
            ..||
Human   219 KEAL 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	30/55 (55%)
		Engrail_1_C_sig	512..542	CDD:431338	3/10 (30%)
HOXC5	NP_061826.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..141		16/94 (17%)
		Antp-type hexapeptide	140..145		0/4 (0%)
		Homeodomain	156..212	CDD:459649	30/55 (55%)