DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment en and Hoxc5

DIOPT Version :9

Sequence 1:	NP_523700.2	Gene:	en / 36240	FlyBaseID:	FBgn0000577	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001101586.1	Gene:	Hoxc5 / 315341	RGDID:	1307584	Length:	222	Species:	Rattus norvegicus

Alignment Length:	199	Identity:	60/199 - (30%)
Similarity:	88/199 - (44%)	Gaps:	24/199 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 SLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPP 389
            |:..||||.:.|......:....:......||:||     :|...||...:.........|....
  Rat    46 SITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAA-----APGHALGRDEAAPLNPGMYSQKAAR 105

  Fly   390 PSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYR--RPKQPKDKTN 452
            |:...|   .:||.:.:.|...|....|.::              |.:.|:..  ..|.......
  Rat   106 PALEER---AKSSGEIKEEQAQTGQPAGLSQ--------------PPAPPQIYPWMTKLHMSHET 153

  Fly   453 DEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKN 517
            |.||.||:::..|...|::||:.|||||.|||.::::.|.|||.||||||||:|.|.||.:..|:
  Rat   154 DGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKS 218

  Fly   518 PLAL 521
            ..||
  Rat   219 KEAL 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeobox	457..510	CDD:278475	28/52 (54%)
en	NP_523700.2	Engrail_1_C_sig	512..541	CDD:287495	3/10 (30%)
Hoxc5	NP_001101586.1	COG5373	65..>142	CDD:227665	17/98 (17%)
Hoxc5	NP_001101586.1	Homeobox	158..212	CDD:395001	28/53 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910