Protein Alignment en and noto

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_571130.1
• Gene: noto / 30260
• ZFINID: ZDB-GENE-990415-75
• Length: 241
• Species: Danio rerio
• Alignment Length: 224
• Identity: 64/224 - (28%)
• Similarity: 94/224 - (41%)
• Gaps: 50/224 - (22%)

  Fly   345 ATSSSSSSSGCSSAASSLNSSPS-----SRLGASGSGVNASSPQPQPIP------PPSAVSRDSG 398
            |||||..|:|.|....:|.:.|.     .|..|..|..|.:......:|      |..|.|:..
Zfish    23 ATSSSKPSTGKSFTIDALLARPDQAEMRERTNAYRSITNQTPVSSSALPLIYSQMPHFAYSQSI- 86

  Fly   399 MESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRP---------KQPKDKTNDE 454
                  .:::||           :|.:.|..........|..|.:.         ...|.|:...
Zfish    87 ------MQTQTG-----------YPVFCYPPYNFQTTCRGAVYAQDAVLAKAAVHSHYKHKSGKS 134

  Fly   455 KRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPL 519
            ||.||:|:::||:||::||...:|:....|..|:|.|.|.|||:|:||||:|.|.:|.  |....
Zfish   135 KRMRTSFTNDQLSRLEKEFARQQYMVGSERFLLASALQLTEAQVKVWFQNRRIKWRKQ--SLEQQ 197

  Fly   520 ALQLMAQGLYNHTTVP------LTKEEEE 542
            ..:|...||    |||      ..:|:||
Zfish   198 QAKLAKLGL----TVPPKSPGSQGREDEE 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	512..542	CDD:431338	8/35 (23%)
noto	NP_571130.1	COG5576	79..>193	CDD:227863	38/133 (29%)
		Homeodomain	135..191	CDD:459649	27/55 (49%)