Protein Alignment en and cog-1

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001022264.1
• Gene: cog-1 / 175149
• WormBaseID: WBGene00000584
• Length: 256
• Species: Caenorhabditis elegans
• Alignment Length: 252
• Identity: 67/252 - (26%)
• Similarity: 110/252 - (43%)
• Gaps: 52/252 - (20%)

  Fly   314 MTQPPLSSSASSLASPPP-----ASNASTISSTSSVATSSSSSSSGCSSAASSLNS------SPS 367
            |::||      .|.:|..     ..::||.|.::.:.....||.||.||...|.:|      |||
 Worm     5 MSEPP------QLTTPDDKDVENRKHSSTYSISNLLLEKKESSPSGSSSEDDSASSNDDDQRSPS 63

  Fly   368 SR-------LGASGSGVNASSP---QPQPIPPPSAVSRDSG-------MESSDDTRSETGSTTTE 415
            :.       ..:|.|..:|:||   ..|.:....||  |.|       ::|..:::|.....|.|
 Worm    64 ATSSFIFPPASSSSSSESATSPTQIMAQLMANGGAV--DPGLQAYFFLLQSQLNSQSMMNRVTQE 126

  Fly   416 GGKNEMWPAWVYCTRYSDRPSSGP--RYRRPKQ--PKDKTNDEKRPRTAFSSEQLARLKREFNEN 476
            .....:....:........||..|  |.:...|  |......:|:.|..|:..|:.:|:|:|.:.
 Worm   127 NVSRALTSFNLLNNLPGALPSLSPMGRLQHSMQLSPNSLNMQKKQSRPTFTGHQIYQLERKFEQT 191

  Fly   477 RYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKK------------STGSKNPLAL 521
            :||....|.||:.||.::|:|:|:||||:|.|.:|            ::|.|:|.:|
 Worm   192 KYLAGADRAQLAQELNMSESQVKVWFQNRRTKWRKKEAADNALVKRGASGDKSPCSL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	512..542	CDD:431338	4/10 (40%)
cog-1	NP_001022264.1	Homeodomain	170..226	CDD:459649	23/55 (42%)