Protein Alignment en and Hoxa5

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_034583.1
• Gene: Hoxa5 / 15402
• MGIID: 96177
• Length: 270
• Species: Mus musculus
• Alignment Length: 236
• Identity: 73/236 - (30%)
• Similarity: 101/236 - (42%)
• Gaps: 61/236 - (25%)

  Fly   307 GQPAAPTMTQPPLSSSASSLASPPP------ASNASTISSTSSVATSSSSSSSGCSSAASSLNSS 365
            |..|||  .:|..|..|:|..||||      |...|..|.:.....:|..:|||.|:.|.|.:.|
Mouse    76 GASAAP--AEPRYSQPATSTHSPPPDPLPCSAVAPSPGSDSHHGGKNSLGNSSGASANAGSTHIS 138

  Fly   366 PSSRLG---ASGSGVNASSPQ------PQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEM 421
            ....:|   |:.....|||.|      |.|.||                           .:.::
Mouse   139 SREGVGTASAAEEDAPASSEQAGAQSEPSPAPP---------------------------AQPQI 176

  Fly   422 WPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQ 486
            :| |:.....|.....||             :.||.|||::..|...|::||:.|||||.|||.:
Mouse   177 YP-WMRKLHISHDNIGGP-------------EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIE 227

  Fly   487 LSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQG 527
            ::..|.|:|.||||||||:|.|.||....|   ::.:.|.|
Mouse   228 IAHALCLSERQIKIWFQNRRMKWKKDNKLK---SMSMAAAG 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	30/55 (55%)
		Engrail_1_C_sig	512..542	CDD:431338	3/16 (19%)
Hoxa5	NP_034583.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		33/127 (26%)
		Antp-type hexapeptide	176..181		2/5 (40%)
		Homeodomain	196..252	CDD:459649	30/55 (55%)