Protein Alignment en and Barx2

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_038828.2
• Gene: Barx2 / 12023
• MGIID: 109617
• Length: 283
• Species: Mus musculus
• Alignment Length: 267
• Identity: 67/267 - (25%)
• Similarity: 104/267 - (38%)
• Gaps: 83/267 - (31%)

  Fly   292 EKSALGSLCKAVSQIGQPAAPTMTQP-PLSSSASSLASPPPASNA----STISSTSSVATSSSSS 351
            ||.:|.|:|.::          :.:| ||.|...|     |:..|    |.|:...:|.:....:
Mouse    40 EKLSLYSVCPSL----------VVRPKPLHSCTGS-----PSLRAYPLLSVITRQPTVISHLVPT 89

  Fly   352 SSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEG 416
            .||.:..   |...|.:  .|..:...|.:|               |.|:...:.|||...|
Mouse    90 GSGLTPV---LTRHPVA--AAEAAAAAAETP---------------GGEALASSESETEQPT--- 131

  Fly   417 GKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTE 481
                                  ||.::|          :|.||.|:..||..|:::|.:.:||:.
Mouse   132 ----------------------PRQKKP----------RRSRTIFTELQLMGLEKKFQKQKYLST 164

  Fly   482 RRRQQLSSELGLNEAQIKIWFQNKRAKIKKST---GSKNPLALQLMAQGLYNHTTVPLTKEEEEL 543
            ..|..|:..|||.:.|:|.|:||:|.|.||..   |.:.|    ...:|.....::| |.||.|.
Mouse   165 PDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAP----TKPKGRPKKNSIP-TSEEIEA 224

  Fly   544 EMRMNGQ 550
            |.:||.|
Mouse   225 EEKMNSQ 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	22/55 (40%)
		Engrail_1_C_sig	512..542	CDD:431338	7/32 (22%)
Barx2	NP_038828.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	107..141		12/83 (14%)
		Homeodomain	138..194	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..283		12/39 (31%)