Protein Alignment en and barhl2

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_012817899.1
• Gene: barhl2 / 100493839
• XenbaseID: XB-GENE-482777
• Length: 359
• Species: Xenopus tropicalis
• Alignment Length: 318
• Identity: 77/318 - (24%)
• Similarity: 116/318 - (36%)
• Gaps: 112/318 - (35%)

  Fly   272 SAANAVIPPPMSSKMSDA-------------NPEKSALGSLCKAVSQIGQPAAP-TMTQPPLSS- 321
            |.|.||.|..:|....||             :.|...:||         .|::| ::|..|:..
 Frog    13 SNAGAVSPGMLSGDFRDARATDFRGQGPLSPDSEIDTVGS---------SPSSPISVTMEPVDQH 68

  Fly   322 --------SASSL--------ASP----PPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSP 366
                    ||..|        .||    ||...::..:||||......
 Frog    69 RLVDSVHHSAQHLQHLHPTQQQSPQQQQPPQLGSAPRTSTSSFLIKDI----------------- 116

  Fly   367 SSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSE----------------------- 408
               ||.| ..:.|.:|....:|.|....:..|..||:..|.:
 Frog   117 ---LGDS-KPLAACAPYSTTVPSPHHTPKHEGNGSSESFRPKLEQEMQDGKGKAEKIREDLHTDI 177

  Fly   409 TGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREF 473
            .|..|.|.|..|:         .|.|.|...|.::|          ::.|||||..||.:|:|.|
 Frog   178 KGHGTKEEGDREI---------TSSRESPPVRAKKP----------RKARTAFSDHQLNQLERSF 223

  Fly   474 NENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQ-GLYN 530
            ...:||:.:.|..|::.|.|.:.|:|.|:||:|.|.|:.|.    :.|:|:|: |.|:
 Frog   224 ERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTA----VGLELLAEAGNYS 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	512..542	CDD:431338	6/20 (30%)
barhl2	XP_012817899.1	Homeodomain	205..261	CDD:459649	23/55 (42%)