DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment inv and RSC58

DIOPT Version :9

Sequence 1:	NP_523699.3	Gene:	inv / 36239	FlyBaseID:	FBgn0001269	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_013133.1	Gene:	RSC58 / 850720	SGDID:	S000004023	Length:	502	Species:	Saccharomyces cerevisiae

Alignment Length:	184	Identity:	27/184 - (14%)
Similarity:	73/184 - (39%)	Gaps:	53/184 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 MHPDCLPLPL---VQPGN----SPQVRE------------------------EEEDEQTECEEQL 74
            :||:...||.   ::.||    :|...|                        |:.:::.:.||.|
Yeast   269 LHPNWYALPTTVWLKYGNYNSWAPSFNENGTVVDSTTRGLIWLERIGYMDLYEKNEKKVKQEELL 333

  Fly    75 NIEDEEV----EEEHDLDLEDPASCCSENSVLSVGQEQSEAAQAALSAQAQARQRLLISQIYRPS 135
            |..:|.:    .:|::.:::..::...::.    |...::|..|:.::::...:...|.::  .:
Yeast   334 NTNEEGINRKQNDENNKNVDGKSNGVQDDG----GDNDNDATIASANSESTENKEQFIIKL--QN 392

  Fly   136 AFSSTATTVLPPSEGPPF---SPEDLLQLPPSTGTFQEEFLRKSQLYAEELMKQ 186
            .::.|.:..:...|...|   :|:.|:         .:..|:..:|..|.::.:
Yeast   393 LYNWTPSNYIGDDEIENFRNGTPDKLV---------SDSLLKLKRLRKERILNK 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
inv	NP_523699.3	Homeobox	474..527	CDD:278475
inv	NP_523699.3	Engrail_1_C_sig	529..554	CDD:287495
RSC58	NP_013133.1	Bromodomain	39..122	CDD:413371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24341
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100