Protein Alignment inv and En1

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_001056699.4
• Gene: En1 / 685360
• RGDID: 1595088
• Length: 409
• Species: Rattus norvegicus
• Alignment Length: 435
• Identity: 152/435 - (34%)
• Similarity: 199/435 - (45%)
• Gaps: 109/435 - (25%)

  Fly   190 LMAAARVNALTAAAAGKQLQMAMAAAAVATVPSGQDALAQLTATALGLGPGGAVHPHQQLLLQRD 254
            |.|.|...|:.||||...|.::::..|..:..|..|::......|....|.....|
  Rat    16 LGAVAAAAAVVAAAAPGGLSLSLSPGASGSSGSDGDSVPVSPQPAPPSPPAAPCLP--------- 71

  Fly   255 QVHHHHHMQNH-----------------------LNNNENLHERALKFSIDNILKADFGSR---- 292
            .:.||.|:..|                       ......|| |...|.|||||:.|||.:
  Rat    72 PLAHHPHLPPHPPPPPPPPPPPPPPQHLAAPAHQPQPAAQLH-RTTNFFIDNILRPDFGCKKEQP 135

  Fly   293 LPKIGALSGNIGGGSVSG--------SSTGSSKNSGNTNGNR-----SPLKAPKKSGKPLNLAQS 344
            ||::...|...|||:..|        |.||:.::..::.|.|     |.|.||..:..|.:.:|.
  Rat   136 LPQLLVASAAAGGGAAGGGSRVERDRSQTGAGRDPVHSLGTRASGAASLLCAPDANCGPPDGSQP 200

  Fly   345 NAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSG-- 407
            ..|..:..|         ...|.:.:.|.:::....:.|......|.|..:|.|:.|::|..|
  Rat   201 ATAVGAGAS---------KAGNPAAAAAAAAAAAAAAVAAAAAAASKPSDSGGGSGGSAGSPGAQ 256

  Fly   408 ------------------------EDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSS 448
                                    .||..|:||||||||||||||||||  ||.||.||
  Rat   257 GAKFPEHNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSG--PRTRKLKK------ 313

  Fly   449 AAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEA 513
                     :|.|       .|||||||||:..||.|||.||..|||:||:|||.|:.||.|||:
  Rat   314 ---------KKNE-------KEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNES 362

  Fly   514 QIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEE 558
            ||||||||||||:||::|.||.|||.|||||||||||..:..::|
  Rat   363 QIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDE 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	38/52 (73%)
		Engrail_1_C_sig	529..554	CDD:287495	17/24 (71%)
En1	XP_001056699.4	Homeobox	323..377	CDD:395001	38/53 (72%)
		Engrail_1_C_sig	378..408	CDD:402244	18/30 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7281
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3716
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002003
OrthoInspector	1	1.000	-	-		mtm9047
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24341
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1139
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.060