Protein Alignment inv and Hoxa13

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001258284.1
• Gene: Hoxa13 / 500129
• RGDID: 1562483
• Length: 386
• Species: Rattus norvegicus
• Alignment Length: 421
• Identity: 91/421 - (21%)
• Similarity: 133/421 - (31%)
• Gaps: 139/421 - (33%)

  Fly   178 LYAEELMKQQMHLMAAARVNAL--------------TAAAAGKQLQMAMAAAAVATVPSGQDALA 228
            |.|:||.|......|||...|.              .|||||....:|.||||.|...:.|  ..
  Rat    26 LVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQ--CR 88

  Fly   229 QLTATALGLGPGGAVHPHQQLLLQRDQVHHHHHMQNHLNNNENLHERALKFSIDNILKADFGS-- 291
            .|.|....|.||.|                                            |.:.|
  Rat    89 NLMAHPAPLAPGAA--------------------------------------------AAYSSAP 109

  Fly   292 -RLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLKA-PKKSGKPLNLAQSNAAANSSLS- 353
             ..|...|.:......:.:.::..||  ||.. |...|..| ..|...|.:.|..:::..::|.
  Rat   110 GEAPPTAAAAAAAAAAAAAAAAAASS--SGGP-GPAGPAGAEAAKQCSPCSAAAQSSSGPAALPY 171

  Fly   354 --FSSS---LANICSNSNDSNSTATSSSTT--------NTSG----------------------- 382
              |.|.   .|.:..:.|...|.|..:|..        :|:|
  Rat   172 GYFGSGYYPCARMGPHPNAIKSCAQPASAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAG 236

  Fly   383 -----APVDLVKSPPPAAGAGATGASGKSGEDSGTPIV----------WPAWVYCTRYSDRPSSG 432
                 .||......|...|.|..|.|  ..|..|.|:.          |...:||.:...:|
  Rat   237 PYHHHQPVPGYLDMPVVPGLGGPGES--RHEPLGLPMESYQPWALPNGWNGQMYCPKEQTQP--- 296

  Fly   433 RSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLT 497
              |...|...|...|             ..:|.......::.|..::..||..|:.|:..|:::|
  Rat   297 --PHLWKSTLPDVVS-------------HPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFIT 346

  Fly   498 EKRRQQLSGELGLNEAQIKIWFQNKRAKLKK 528
            :.:|:::|....|:|.|:.|||||:|.|.||
  Rat   347 KDKRRRISATTNLSERQVTIWFQNRRVKEKK 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	19/55 (35%)
		Engrail_1_C_sig	529..554	CDD:431338	91/421 (22%)
Hoxa13	NP_001258284.1	HoxA13_N	<151..222	CDD:463521	13/70 (19%)
		Homeodomain	321..377	CDD:459649	19/55 (35%)