Protein Alignment inv and En2

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001102684.1
• Gene: En2 / 499964
• RGDID: 1561842
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 343
• Identity: 134/343 - (39%)
• Similarity: 160/343 - (46%)
• Gaps: 81/343 - (23%)

  Fly   236 GLGPGGAVHPHQQ-----------LLLQRDQVHHHHHMQNHLNNNENLHERALKFSIDNILKADF 289
            |.|.||...|...           .:||....|.|.|             |...|.|||||:.:|
  Rat    24 GGGSGGGSSPSDSDTGRRRALMLPAVLQAPGNHQHPH-------------RITNFFIDNILRPEF 75

  Fly   290 GSR-------LPKIGALSGNIGGGSV--SGSSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSN 345
            |.|       ....||..|..|.||.  .|.:.|:.:..|......:|..|| .:|.||:.|..:
  Rat    76 GRRKDAGTCCAGAGGARGGEGGAGSTEGGGGADGAEQILGARESRPNPACAP-SAGGPLSGASGD 139

  Fly   346 AAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGEDS 410
            .||               :....:.|.:........|.|...:.....|.|.|....|..|..||
  Rat   140 PAA---------------DGEGGSKTLSLHGGAKKPGDPGGSLDGALKARGLGGGDLSVSSDSDS 189

  Fly   411 --------GTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGG 467
                    ..|::|||||||||||||||||  ||:|||||...:.
  Rat   190 SQASATLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKNPNK-------------------- 232

  Fly   468 VPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGT 532
              |||||||||:..||.|||.||..||||||:|||.|:.||.|||:||||||||||||:||::|.
  Rat   233 --EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGN 295

  Fly   533 KNPLALQLMAQGLYNHST 550
            ||.||:.|||||||||||
  Rat   296 KNTLAVHLMAQGLYNHST 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	39/52 (75%)
		Engrail_1_C_sig	529..554	CDD:287495	16/22 (73%)
En2	NP_001102684.1	Homeobox	237..290	CDD:278475	39/52 (75%)
		Engrail_1_C_sig	292..321	CDD:287495	16/22 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7281
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3716
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002003
OrthoInspector	1	1.000	-	-		mtm9047
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24341
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1139
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.060