Protein Alignment inv and nkx6.1

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Alignment Length: 241
• Identity: 67/241 - (27%)
• Similarity: 96/241 - (39%)
• Gaps: 62/241 - (25%)

  Fly   311 SSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICS-----NSND--S 368
            ||||.:.::..|      ..:|...|.|  ::......:|.||..:| |..|:     ..||  |
Zfish    42 SSTGPASSTSPT------ATSPNPGGIP--VSSPGIKTSSGLSALAS-AQQCAIATPHGINDILS 97

  Fly   369 NSTATSSSTTNTSGAPVDLVKSPPPAAG------AGA----------TGASGKSGEDSGTPIVWP 417
            ..:...|.....||.|.....||||..|      |.|          |...|:      |||.||
Zfish    98 RPSVACSPAGILSGLPRFSSLSPPPPPGLYFSPSAAAVAVARYPKPLTELPGR------TPIFWP 156

  Fly   418 AWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQ 482
            ..:....:.|         ||....|..:|..       ::|    ||    :.|..|..|||.|
Zfish   157 GVMQSPHWRD---------ARFACSPHQNSVL-------LDK----DG----KRKHTRPTFSGQQ 197

  Fly   483 LARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK 528
            :..|:..|.:.:||....|.:|:..||:.|:|:|:||||:|.|.:|
Zfish   198 IFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	67/241 (28%)
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	23/57 (40%)