DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inv and MEOX1

DIOPT Version :9

Sequence 1:	NP_523699.3	Gene:	inv / 36239	FlyBaseID:	FBgn0001269	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_004518.1	Gene:	MEOX1 / 4222	HGNCID:	7013	Length:	254	Species:	Homo sapiens

Alignment Length:	145	Identity:	49/145 - (33%)
Similarity:	67/145 - (46%)	Gaps:	35/145 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 PAWVYCTRYSD---RPSSGRSPRARKPKKPATSS----SAAGGGGG--GV--------------- 457
            |.|.:  ..||   ||:||   .|...|:..|||    ...||.|.  ||
Human    92 PNWHF--PVSDARRRPNSG---PAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRR 151

  Fly   458 --EKGEAADGGGVPED----KRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIK 516
              |..:..:..|.||.    ::.||||:..||..|:.||..:.|||..||.:::..|.|:|.|:|
Human   152 RKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVK 216

  Fly   517 IWFQNKRAKLKKSSG 531
            :||||:|.|.|:..|
Human   217 VWFQNRRMKWKRVKG 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	25/52 (48%)
inv	NP_523699.3	Engrail_1_C_sig	529..554	CDD:287495	1/3 (33%)
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	86..178		24/90 (27%)
		Homeobox	175..227	CDD:306543	25/51 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..254		2/5 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910