Protein Alignment inv and PDX1

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_000200.1
• Gene: PDX1 / 3651
• HGNCID: 6107
• Length: 283
• Species: Homo sapiens
• Alignment Length: 176
• Identity: 52/176 - (29%)
• Similarity: 68/176 - (38%)
• Gaps: 45/176 - (25%)

  Fly   391 PPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSD------------------RPSSGRSPRA 437
            |||....||.||.    |....|.:.|..|  ...:|                  .|.:|..|..
Human    45 PPPHPFPGALGAL----EQGSPPDISPYEV--PPLADDPAVAHLHHHLPAQLALPHPPAGPFPEG 103

  Fly   438 RKP---------------KKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLK 487
            .:|               .|...:.:..|...||....|.      .|:||.|||::..||..|:
Human   104 AEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEP------EENKRTRTAYTRAQLLELE 162

  Fly   488 HEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTK 533
            .||..|:|::..||.:|:..|.|.|..|||||||:|.|.||....|
Human   163 KEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKK 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	25/52 (48%)
		Engrail_1_C_sig	529..554	CDD:287495	1/5 (20%)
PDX1	NP_000200.1	Transactivation domain. /evidence=ECO:0000250	13..73		11/33 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..71		11/31 (35%)
		Antp-type hexapeptide	118..123		0/4 (0%)
		Homeobox	149..202	CDD:278475	25/52 (48%)
		Nuclear localization signal. /evidence=ECO:0000250	197..203		2/5 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..283		3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910