Protein Alignment inv and HOXC8

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 70/333 - (21%)
• Similarity: 107/333 - (32%)
• Gaps: 149/333 - (44%)

  Fly   234 ALGLGPGGAVHPHQQLLLQRDQVHHHHHMQNHLNNNENLHERALKFSIDNILKADFGSRLPKIGA 298
            ||..||||:....|         |..||:|:..::
Human    37 ALVYGPGGSAPGFQ---------HASHHVQDFFHH------------------------------ 62

  Fly   299 LSGNIGGGSVSGSSTGSSKNSGNTNGNRSPL----KAPKKSGKPLNLAQSNAAANSSLSFSSSLA 359
                 |...:|.|....:..|.:.:|:.|..    ..|::|   |..||..|   |.:.:..
Human    63 -----GTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQS---LYGAQQEA---SVVQYPD--- 113

  Fly   360 NICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTR 424
              |.:|.::||:.                             ..|...::|...:::| |:
Human   114 --CKSSANTNSSE-----------------------------GQGHLNQNSSPSLMFP-WM---- 142

  Fly   425 YSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHE 489
                          :|..|...|.                          |..:|..|...|:.|
Human   143 --------------RPHAPGRRSG--------------------------RQTYSRYQTLELEKE 167

  Fly   490 FNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLT 554
            |..|.|||.|||.::|..|||.|.|:||||||:|.|.||.:                |...:|..
Human   168 FLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN----------------NKDKLPGA 216

  Fly   555 REEEELQE 562
            |:||:::|
Human   217 RDEEKVEE 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	27/52 (52%)
		Engrail_1_C_sig	529..554	CDD:287495	2/24 (8%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		11/113 (10%)
		Antp-type hexapeptide	138..143		2/23 (9%)
		Homeobox	153..205	CDD:306543	27/51 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		7/35 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910