DRSC/TRiP Functional Genomics Resources

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Protein Alignment inv and HOXC4

DIOPT Version :9

Sequence 1:NP_523699.3 Gene:inv / 36239 FlyBaseID:FBgn0001269 Length:576 Species:Drosophila melanogaster
Sequence 2:NP_055435.2 Gene:HOXC4 / 3221 HGNCID:5126 Length:264 Species:Homo sapiens


Alignment Length:193 Identity:58/193 - (30%)
Similarity:84/193 - (43%) Gaps:51/193 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   391 PPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYS-DRPSSGRSPRARKP------KKPATSSS 448
            |.|.:||.|:.:              ||...|::.: |.|||..|   ::|      ||...|:.
Human   100 PAPLSGASASPS--------------PAPPACSQPAPDHPSSAAS---KQPIVYPWMKKIHVSTV 147

  Fly   449 AAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEA 513
            .....||              |.||.|||::..|:..|:.||:.|||||.:||.:::..|.|:|.
Human   148 NPNYNGG--------------EPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSER 198

  Fly   514 QIKIWFQNKRAKLKKSSGTKN------------PLALQLMAQGL-YNHSTIPLTREEEELQEL 563
            ||||||||:|.|.||.....|            |..|.....|. .:||......|::..:::
Human   199 QIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDI 261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
invNP_523699.3 Homeobox 474..527 CDD:278475 27/52 (52%)
Engrail_1_C_sig 529..554 CDD:287495 6/37 (16%)
HOXC4NP_055435.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 19..130 12/43 (28%)
Antp-type hexapeptide 135..140 0/4 (0%)
Homeobox 159..213 CDD:395001 27/53 (51%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 214..264 7/48 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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