Protein Alignment inv and HOXB7

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 70/245 - (28%)
• Similarity: 97/245 - (39%)
• Gaps: 64/245 - (26%)

  Fly   350 SSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGAT----------GASG 404
            |||.::::|.:....|  |:..||.:....||.|.....:.|...||:||:          |..|
Human     2 SSLYYANTLFSKYPAS--SSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGG 64

  Fly   405 KSGEDSGTPIVWPAWVYCTRYSDRPSS-----------------GRSPRARKPKKPATSSSAAGG 452
            .:|:.:       |.||...|...|||                 |.|.:|...|:...|..||..
Human    65 MAGQSA-------AGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAES 122

  Fly   453 G--------GGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELG 509
            .        ..|.::            ||.|..::..|...|:.||:.|||||.:||.:::..|.
Human   123 NFRIYPWMRSSGTDR------------KRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLC 175

  Fly   510 LNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEEE 559
            |.|.||||||||:|.|.||.:.|..|        |...........||||
Human   176 LTERQIKIWFQNRRMKWKKENKTAGP--------GTTGQDRAEAEEEEEE 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	529..554	CDD:431338	3/24 (13%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		0/4 (0%)
		Homeodomain	138..194	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		6/30 (20%)