Protein Alignment inv and HOXB3

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_016880049.1
• Gene: HOXB3 / 3213
• HGNCID: 5114
• Length: 578
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 112/417 - (26%)
• Similarity: 142/417 - (34%)
• Gaps: 151/417 - (36%)

  Fly   276 ALKFSIDNILKADFGSRLP----KIGALSGNI------------------------GGGSVSGSS 312
            |||..:....:...|||.|    :.|:.|||.                        |||.|..|:
Human    26 ALKARVQLGARRARGSRSPARPGRSGSFSGNWRLPRPECQIRALLGPWRPNKAGGGGGGGVGASA 90

  Fly   313 TGSSKNSGNTNG-----------------NRSP---------------------LKAPKKSGKPL 339
            :|.....|.|.|                 .|||                     .:.|:.||:|.
Human    91 SGPLPQLGGTLGGCWGLLRVERLGCGWLRRRSPSLGRGSGAWQSAPARTQRPAARRCPRPSGRPH 155

  Fly   340 NLAQSNAAANSSLS---------FSSSLA------------NICSNSNDSNSTATSSSTTNTSG- 382
            .....:.||.|...         ..||:|            :.||..:..|: |..:.:...:|
Human   156 RRGDLSPAARSGARCEYILCLPVLPSSVAKAATHLEGDYQRSACSLQSLGNA-APHAKSKELNGS 219

  Fly   383 ------APVDLVK---SPPP-AAGAGATGASGKSG--EDSGTPIVWPA-----------WVYCTR 424
                  ||..|..   |||| ||...||..|...|  ..||.|...|.           |:
Human   220 CMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWM---- 280

  Fly   425 YSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGG-------------GVPEDKRPRT 476
                 ...|.....|...|.|:....||||||...|....||             |....||.||
Human   281 -----KESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRART 340

  Fly   477 AFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK---------SSGT 532
            |::..||..|:.||:.||||...||.:::..|.|:|.||||||||:|.|.||         |||.
Human   341 AYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGG 405

  Fly   533 KNPLA-----LQLMAQGLYN--HSTIP 552
            .:|..     :|..| |..|  ||..|
Human   406 PSPAGSPPQPMQSTA-GFMNALHSMTP 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	27/52 (52%)
		Engrail_1_C_sig	529..554	CDD:287495	11/31 (35%)
HOXB3	XP_016880049.1	Homeobox	339..391	CDD:278475	27/51 (53%)
		DUF4074	513..576	CDD:290032

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910