Protein Alignment inv and MNX1

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_005506.3
• Gene: MNX1 / 3110
• HGNCID: 4979
• Length: 401
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 85/403 - (21%)
• Similarity: 120/403 - (29%)
• Gaps: 177/403 - (43%)

  Fly   274 ERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLKAPKKSGKP 338
            |::..|.||.:|..|                                       |.:|......|
Human     2 EKSKNFRIDALLAVD---------------------------------------PPRAASAQSAP 27

  Fly   339 LNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVK----SPP------- 392
            |.|..|.|||.|..............::.|.|.|:|    ....||.|.::    |||
Human    28 LALVTSLAAAASGTGGGGGGGGASGGTSGSCSPASS----EPPAAPADRLRAESPSPPRLLAAHC 88

  Fly   393 ---PAAG-AGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGG 453
               |..| .||.|..|.:|...|.|          .:...|.:..:..|      |.:::||||.
Human    89 ALLPKPGFLGAGGGGGGTGGGHGGP----------HHHAHPGAAAAAAA------AAAAAAAGGL 137

  Fly   454 GGGVEKGEAADGGGVPED----------------------------------------------- 471
            ..|:..|.|..|.|:|..
Human   138 ALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIK 202

  Fly   472 ---------------------------------------KRPRTAFSGTQLARLKHEFNENRYLT 497
                                                   :||||||:..||..|:|:|..|:||:
Human   203 LGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLS 267

  Fly   498 EKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEEELQE 562
            ..:|.:::..|.|.|.|:||||||:|.|.|:|...|...|                 :|.|:.:.
Human   268 RPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAA-----------------QEAEKQKG 315

  Fly   563 LQEAASAAAAKEP 575
            ....|....|:||
Human   316 GGGGAGKGGAEEP 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	26/52 (50%)
		Engrail_1_C_sig	529..554	CDD:287495	3/24 (13%)
MNX1	NP_005506.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..78		9/44 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..120		5/28 (18%)
		Homeobox	244..297	CDD:278475	26/52 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..401		9/47 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910