DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inv and hoxb4a

DIOPT Version :9

Sequence 1:	NP_523699.3	Gene:	inv / 36239	FlyBaseID:	FBgn0001269	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_571193.1	Gene:	hoxb4a / 30340	ZFINID:	ZDB-GENE-990415-105	Length:	246	Species:	Danio rerio

Alignment Length:	165	Identity:	52/165 - (31%)
Similarity:	74/165 - (44%)	Gaps:	35/165 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 STATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRS 434
            :||.|:.....|.....:..|||||.|...|..:..:......|:|:| |:
Zfish    85 TTALSTPLPEPSHHCDSVTPSPPPACGQTPTSQNTSTVSSRKDPVVYP-WM-------------- 134

  Fly   435 PRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEK 499
               :|......|.:.:||                 |.||.|||::..|:..|:.||:.|||||.:
Zfish   135 ---KKVHVNIVSPNYSGG-----------------EPKRSRTAYTRQQVLELEKEFHYNRYLTRR 179

  Fly   500 RRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKN 534
            ||.:::..|.|:|.||||||||:|.|.||.....|
Zfish   180 RRVEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPN 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	27/52 (52%)
inv	NP_523699.3	Engrail_1_C_sig	529..554	CDD:287495	1/6 (17%)
hoxb4a	NP_571193.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..125		11/39 (28%)
		Antp-type hexapeptide	130..135		3/22 (14%)
		Homeobox	154..207	CDD:278475	27/52 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..246		1/5 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910