Protein Alignment inv and Hoxd3

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001257967.1
• Gene: Hoxd3 / 288152
• RGDID: 1588601
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 309
• Identity: 80/309 - (25%)
• Similarity: 109/309 - (35%)
• Gaps: 104/309 - (33%)

  Fly   283 NILKADFGS-----------RLPKIGALSGNIGGGSVSGSSTGSSKNSGNTN---GNRSPLKAPK 333
            |.|.:|:.|           |.|   |..|....||.....||:|:..|..|   |..|..:.|:
  Rat    57 NSLDSDYPSSACSIQSSAPLRAP---AHKGAELNGSCMRPGTGNSQGGGGGNQPPGLNSEQQPPQ 118

  Fly   334 KSGKPLNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNT-SGAPVDLVKSPPPAAGA 397
            ....|                               .|...||.||. ||.|....|..|.|:.:
  Rat   119 PPPPP-------------------------------PTLPPSSPTNPGSGVPAKKTKGGPNASSS 152

  Fly   398 GATGASGKSGEDSGTPIVWPAWVYCTRYSDR-----PSSGRSPRARKPKKPATSSSAAGGGGGGV 457
            .:|.:..          ::| |:..:|.:.:     .:||.:...:.|..||:
  Rat   153 SSTISKQ----------IFP-WMKESRQNSKQKNSCATSGENCEDKSPPGPAS------------ 194

  Fly   458 EKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNK 522
                          ||.|||::..||..|:.||:.||||...||.:::..|.|.|.||||||||:
  Rat   195 --------------KRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNR 245

  Fly   523 RAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEEELQELQEAASAAA 571
            |.|.||....|..|           ||  |..:..|....|..||...|
  Rat   246 RMKYKKDQKAKGIL-----------HS--PAGQSPERSPPLGGAAGHVA 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	29/55 (53%)
		Engrail_1_C_sig	529..554	CDD:431338	5/24 (21%)
Hoxd3	NP_001257967.1	Homeodomain	195..251	CDD:459649	29/55 (53%)
		DUF4074	369..430	CDD:463833