Protein Alignment inv and tlx3b

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_739572.2
• Gene: tlx3b / 266965
• ZFINID: ZDB-GENE-021021-1
• Length: 300
• Species: Danio rerio
• Alignment Length: 324
• Identity: 79/324 - (24%)
• Similarity: 126/324 - (38%)
• Gaps: 75/324 - (23%)

  Fly   273 HERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLKAPKKSGK 337
            || .:.|.||.||                       ||:...|.:|| ..|.:.|...:...||.
Zfish    21 HE-PISFGIDQIL-----------------------SGTDQESQQNS-TRNSSESSSGSSSASGG 60

  Fly   338 PLNL-AQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSP---PPAAGAG 398
            ..:| :.:.|:|....:.:.:...|.:...:|     |....|.:.||..:::.|   |.||...
Zfish    61 CYHLGSPTGASATPYTTLTGTFHGIAAPYEES-----SPYGMNLTLAPGGVIRVPAHRPLAAAVP 120

  Fly   399 ATGASGKSGEDSGTPIVWPAWVYCTRYS-DRPSSGRSP--RARKPKKPATSSSAAGGGGGGVEKG 460
            ...||...|..|   :.:|......|:: ||.::..:|  .||:...|..:.:.
Zfish   121 PPMASAVPGLGS---LSFPWMESSQRFAKDRFAAALTPFTVARRIGHPYQNRTP----------- 171

  Fly   461 EAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAK 525
                    |:.|:|||:||..|:..|:..|:..:||....|..|:..|.:.:||:|.||||:|.|
Zfish   172 --------PKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKTLKMTDAQVKTWFQNRRTK 228

  Fly   526 LKKSSGTK--------NPLALQLMAQGLYNH-----STIPLTREEEE---LQELQEAASAAAAK 573
            .::.:..:        |.|.:||........     .|.||......   ||.||..||..::|
Zfish   229 WRRQTAEEREAERQQANRLMIQLQHDAFQKSLTDSVPTDPLCIHNSSLFALQNLQPWASEESSK 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	6/37 (16%)
tlx3b	NP_739572.2	Homeodomain	175..231	CDD:459649	23/55 (42%)