Protein Alignment inv and GBX1

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001092304.1
• Gene: GBX1 / 2636
• HGNCID: 4185
• Length: 363
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 84/329 - (25%)
• Similarity: 120/329 - (36%)
• Gaps: 92/329 - (27%)

  Fly   297 GALSGNIGGGSVSGSSTGSS---------KNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAA---- 348
            |:..|..|||...|..|..|         ..||:......|:..|.   :||.|.|:.|.|
Human     7 GSAPGGNGGGGGGGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMPY---RPLVLPQALAPAPLPA 68

  Fly   349 -----NSSLSFSSSLAN-ICSNSNDSNSTATSSSTTNTSGA-PVDLVKSP---PPAAGAGATGAS 403
                 ....||:..|.| .|:....:..:..:.:|...|.| |.|....|   ..||.|.|..|:
Human    69 GLPPLAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQELAAAAAAAAATAA 133

  Fly   404 GKSGEDSG--------------------TPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSS 448
            ..:.|..|                    .|...|...:...:...|:.|:...:.:.|..|::..
Human   134 RNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEASAGD 198

  Fly   449 AAG------GGGGGVE----------------------KGEAADGG--GVP----------EDKR 473
            .||      |.||..|                      ||....|.  |.|          :.:|
Human   199 PAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSLGTGAEEGAPVTAGVTAPGGKSRR 263

  Fly   474 PRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK------SSGT 532
            .||||:..||..|:.||:..:||:...|.|::..|.|:|.|:||||||:|||.|:      ||.:
Human   264 RRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRS 328

  Fly   533 KNPL 536
            ..|:
Human   329 GEPV 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	26/52 (50%)
		Engrail_1_C_sig	529..554	CDD:287495	3/8 (38%)
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		8/23 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..265		22/136 (16%)
		Homeobox	264..317	CDD:306543	26/52 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910