Protein Alignment inv and Gbx1

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001258382.1
• Gene: Gbx1 / 246149
• RGDID: 621864
• Length: 425
• Species: Rattus norvegicus
• Alignment Length: 349
• Identity: 90/349 - (25%)
• Similarity: 129/349 - (36%)
• Gaps: 106/349 - (30%)

  Fly   294 PKIGALSGNIGGGS-----VSGSSTGSSKNSGNTNGNRSPLKA-----PKKSG------------ 336
            |.:.|.....|.||     ..|.:.|.|..||...|....:.:     |.:||
  Rat    46 PCVSAPGARRGPGSAMQRAAGGGAPGGSGGSGGGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMP 110

  Fly   337 -KPLNLAQSNAAA---------NSSLSFSSSLAN-ICSNSNDSNSTATSSSTTNTSGA-PVDLVK 389
             :||.|.|:.|.|         ....||:..|:| .|:....:..:..:.:|...|.| |.|...
  Rat   111 YRPLVLPQALAPAPLPAGLPPLAPLASFAGRLSNTFCAGLGQAVPSMVALTTALPSFAEPPDAYY 175

  Fly   390 SPPP-AAGAGATGASGKSGEDSGTPI-----------VWPAWVYCTR---------------YSD 427
            .||. ||.|.|..||..|..:...|.           :.||....|.               :..
  Rat   176 GPPELAAAAAAAAASTVSRSNPEPPARRTDGALDADELLPAREKVTEPPPPPPPPPPHFSETFPS 240

  Fly   428 RPSSGR--------------SPRARKPKKPAT---------SSSAAGGG-------------GGG 456
            .|:.|:              .|...:|::..:         .|||.|.|             |.|
  Rat   241 LPAEGKVYSSDEEKLEPPAGEPAGSEPEEEGSGGDSEDSFLDSSAGGPGALLGPKPKLKGSLGTG 305

  Fly   457 VEKG-EAADGGGVP--EDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIW 518
            .|:| ..|.|...|  :.:|.||||:..||..|:.||:..:||:...|.|::..|.|:|.|:|||
  Rat   306 AEEGTPVATGVTTPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIW 370

  Fly   519 FQNKRAKLKK------SSGTKNPL 536
            |||:|||.|:      ||.:..|:
  Rat   371 FQNRRAKWKRIKAGNVSSRSGEPV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	529..554	CDD:431338	3/8 (38%)
Gbx1	NP_001258382.1	Homeodomain	324..380	CDD:459649	27/55 (49%)