Protein Alignment inv and Pdx1

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 192
• Identity: 61/192 - (31%)
• Similarity: 78/192 - (40%)
• Gaps: 60/192 - (31%)

  Fly   373 TSSSTTNTSGAPVDLVKSP---PPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRS 434
            |||..:...|:|.|:  ||   ||.|.....||.....        .||.:...    .|..|..
Mouse    51 TSSLGSLEQGSPPDI--SPYEVPPLASDDPAGAHLHHH--------LPAQLGLA----HPPPGPF 101

  Fly   435 PRARKPKKPATSSSAAGGGGGGVE--------------------KGEAADGG--GVPED-KRPRT 476
            |...:|              ||:|                    ||:.|.|.  ..||: ||.||
Mouse   102 PNGTEP--------------GGLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYTAEPEENKRTRT 152

  Fly   477 AFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK------SSGT 532
            |::..||..|:.||..|:|::..||.:|:..|.|.|..|||||||:|.|.||      ||||
Mouse   153 AYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRSSGT 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	529..554	CDD:431338	4/4 (100%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		9/23 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		22/92 (24%)
		Antp-type hexapeptide	119..124		0/4 (0%)
		Homeodomain	148..204	CDD:459649	27/55 (49%)
		Nuclear localization signal	198..204		2/5 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		6/13 (46%)