Protein Alignment inv and Meox2

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_032610.1
• Gene: Meox2 / 17286
• MGIID: 103219
• Length: 303
• Species: Mus musculus
• Alignment Length: 335
• Identity: 73/335 - (21%)
• Similarity: 114/335 - (34%)
• Gaps: 119/335 - (35%)

  Fly   214 AAAVATVPSGQDALA------QLTATALGLGPGGAV---HPHQQLLL--QRDQVHHHHHMQNHLN 267
            |.|....|..|.:||      .::...|.......:   :|:::.:.  |..:.|||||..:|.:
Mouse    14 ATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHH 78

  Fly   268 NNENLHERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLKAP 332
            :.:..|:                       ||..|                          ...|
Mouse    79 HQQQQHQ-----------------------ALQSN--------------------------WHLP 94

  Fly   333 KKSGKPLNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPP-AAG 396
            :.|..|       :||..||.....                       ||.|.:|..|||. .:.
Mouse    95 QMSSPP-------SAARHSLCLQPD-----------------------SGGPPELGSSPPVLCSN 129

  Fly   397 AGATGASGKSGE-----DSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGG 456
            :.:.|:|..:|.     |.|...:.||.|             ..|:...:|..:|.|..|.....
Mouse   130 SSSLGSSTPTGAACAPGDYGRQALSPADV-------------EKRSGSKRKSDSSDSQEGNYKSE 181

  Fly   457 VEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQN 521
            |..          :.::.||||:..|:..|:.||..:.|||..||.:::..|.|.|.|:|:||||
Mouse   182 VNS----------KPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQN 236

  Fly   522 KRAKLKKSSG 531
            :|.|.|:..|
Mouse   237 RRMKWKRVKG 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	24/55 (44%)
		Engrail_1_C_sig	529..554	CDD:431338	1/3 (33%)
Meox2	NP_032610.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..191		39/229 (17%)
		Homeodomain	187..243	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..303