Protein Alignment inv and Hoxa5

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_034583.1
• Gene: Hoxa5 / 15402
• MGIID: 96177
• Length: 270
• Species: Mus musculus
• Alignment Length: 326
• Identity: 84/326 - (25%)
• Similarity: 119/326 - (36%)
• Gaps: 88/326 - (26%)

  Fly   236 GLGPGGAVHPHQQLLLQRDQVHHHHHMQNHLNNNENLHERALKFSIDNILKADFGSRLPKIGALS 300
            |..|.|   |..||          |:..:|.:.:|...:.|                    ...|
Mouse    11 GRYPNG---PDYQL----------HNYGDHSSVSEQFRDSA--------------------SMHS 42

  Fly   301 GNIGGGSVSGS--STGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICS 363
            |..|.| .:|.  |.|.|.:....:|.|:...|...|..|.....|..|.::.......|.  ||
Mouse    43 GRYGYG-YNGMDLSVGRSGSGHFGSGERARSYAAGASAAPAEPRYSQPATSTHSPPPDPLP--CS 104

  Fly   364 NSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDR 428
                  :.|.|..:.:..|....|..|...:|.||:|..|.:.|..:.:          ....|.
Mouse   105 ------AVAPSPGSDSHHGGKNSLGNSSGASANAGSTHISSREGVGTAS----------AAEEDA 153

  Fly   429 PSSGRSPRARKPKKPA---------------TSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAF 478
            |:|.....|:....||               .|....||                ||.||.|||:
Mouse   154 PASSEQAGAQSEPSPAPPAQPQIYPWMRKLHISHDNIGG----------------PEGKRARTAY 202

  Fly   479 SGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQ 543
            :..|...|:.||:.|||||.:||.:::..|.|:|.||||||||:|.|.||.:..|   ::.:.|.
Mouse   203 TRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLK---SMSMAAA 264

  Fly   544 G 544
            |
Mouse   265 G 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	29/55 (53%)
		Engrail_1_C_sig	529..554	CDD:431338	3/16 (19%)
Hoxa5	NP_034583.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		24/117 (21%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	196..252	CDD:459649	29/55 (53%)