Protein Alignment inv and En2

DIOPT Version :9

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_034264.1
• Gene: En2 / 13799
• MGIID: 95390
• Length: 324
• Species: Mus musculus
• Alignment Length: 370
• Identity: 136/370 - (36%)
• Similarity: 169/370 - (45%)
• Gaps: 85/370 - (22%)

  Fly   200 TAAAAGKQLQMAMAAAAVATVPSGQDALAQLTATALGLGPGGAVHPHQQ-----------LLLQR 253
            |||.|.:|.:           ||.            |.|.||...|...           .:||.
Mouse    11 TAAEAQRQPE-----------PSS------------GGGSGGGSSPSDSDTGRRRALMLPEVLQA 52

  Fly   254 DQVHHHHHMQNHLNNNENLHERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSSKN 318
            ...|.|.|             |...|.|||||:.:||.| ...|......||........|:::.
Mouse    53 PGNHQHPH-------------RITNFFIDNILRPEFGRR-KDAGTCCAGAGGARGGEGGAGTTEG 103

  Fly   319 SGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGA 383
            .|...|....|...::| :| |.|   .|.::..:.|::..:...:....:.|.:........|.
Mouse   104 GGGGAGGAEQLLGARES-RP-NPA---CAPSAGGTLSAAAGDPAVDGEGGSKTLSLHGGAKKPGD 163

  Fly   384 PVDLVKSPPPAAGAGATGASGKSGEDS--------GTPIVWPAWVYCTRYSDRPSSGRSPRARKP 440
            |...:.....|.|.|....|..|..||        ..|::|||||||||||||||||  ||:|||
Mouse   164 PGGSLDGVLKARGLGGGDLSVSSDSDSSQASATLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKP 226

  Fly   441 KKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLS 505
            ||...:.                      |||||||||:..||.|||.||..||||||:|||.|:
Mouse   227 KKKNPNK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLA 269

  Fly   506 GELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHST 550
            .||.|||:||||||||||||:||::|.||.||:.|||||||||||
Mouse   270 QELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHST 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	39/52 (75%)
		Engrail_1_C_sig	529..554	CDD:287495	16/22 (73%)
En2	NP_034264.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		15/70 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..174		15/89 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..240		18/48 (38%)
		Homeobox	238..291	CDD:278475	39/52 (75%)
		Engrail_1_C_sig	293..322	CDD:287495	16/22 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7450
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002003
OrthoInspector	1	1.000	-	-		mtm8801
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24341
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2569
SonicParanoid	1	1.000	-	-		X1139
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.040