DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inv and Hoxa3

DIOPT Version :9

Sequence 1:	NP_523699.3	Gene:	inv / 36239	FlyBaseID:	FBgn0001269	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001300749.1	Gene:	Hoxa3 / 103690130	RGDID:	1561431	Length:	444	Species:	Rattus norvegicus

Alignment Length:	162	Identity:	54/162 - (33%)
Similarity:	80/162 - (49%)	Gaps:	39/162 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 SPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRS-----PRARKPKKPATSSSA 449
            |||.:|.:..|.||     .:.:|::           :.|:.|:.     ..:|:..|..||.|:
  Rat   127 SPPQSANSNPTPAS-----TAKSPLL-----------NSPTVGKQIFPWMKESRQNTKQKTSGSS 175

  Fly   450 AGGGGGGVEK--GEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNE 512
            :|....|.:.  |:|:       .||.|||::..||..|:.||:.||||...||.:::..|.|.|
  Rat   176 SGESCAGDKSPPGQAS-------SKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTE 233

  Fly   513 AQIKIWFQNKRAKLKK---------SSGTKNP 535
            .||||||||:|.|.||         |||.::|
  Rat   234 RQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeobox	474..527	CDD:278475	27/52 (52%)
inv	NP_523699.3	Engrail_1_C_sig	529..554	CDD:287495	4/7 (57%)
Hoxa3	NP_001300749.1	COG5576	<182..309	CDD:227863	38/91 (42%)
		Homeobox	196..249	CDD:395001	27/52 (52%)
		DUF4074	379..442	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910