Protein Alignment E(Pc) and epc1a

DIOPT Version :9

• Sequence 1: NP_001260897.1
• Gene: E(Pc) / 36238
• FlyBaseID: FBgn0000581
• Length: 2097
• Species: Drosophila melanogaster
• Sequence 2: XP_695062.2
• Gene: epc1a / 566686
• ZFINID: ZDB-GENE-070629-5
• Length: 796
• Species: Danio rerio
• Alignment Length: 927
• Identity: 301/927 - (32%)
• Similarity: 446/927 - (48%)
• Gaps: 212/927 - (22%)

  Fly     1 MSKLSFRARHLDPSKQMPIYLAEELPDLPEYSAINRAVPQMPSGMEKEEESEHHLQRAICT---- 61
            |||||||||.||..|.:||:..|:||||.||::|||||||||:||||:||.||||||||..
Zfish     1 MSKLSFRARALDALKPLPIFRCEDLPDLHEYASINRAVPQMPTGMEKDEELEHHLQRAISAQQVY 65

  Fly    62 -----GLIIPTPEVLQTDQPFYDAYYPPDYKMPRQMIHMQPLGLDTEVPDYDMDSADEDWLSQ-Q 120
                 .::||.||. :::..:||:.||.|:|||:|:||:||..||||.||||:|..||.:::: :
Zfish    66 GEKRDNMVIPVPEA-ESNIAYYDSLYPGDFKMPKQLIHIQPFSLDTEQPDYDLDLEDEVFVNKLK 129

  Fly   121 QRLELTELKFEQMMDRLEKSSGQTVVTLNEAKSLLNQDDETSISVYDYWLNKR-LKMQHPLILTV 184
            ::||:..|:||:|:|||||.|||.:|||.|||.||.:|||....|::||..|| |.....||..:
Zfish   130 KKLEVEALQFEEMIDRLEKGSGQQLVTLQEAKLLLKEDDELIREVFEYWSRKRKLSKYGSLIPNI 194

  Fly   185 KTESRPGASSNNPYLAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLQRATTILEMVRRREETKR 249
            :.|.|.|:|:|:||:||||||||||||||||||||||||||||||||.||.|||||:::||::||
Zfish   195 RQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKKREKSKR 259

  Fly   250 DHLKMTVNIFEKRVEMRDFNGAVYSELNSQYKNTRPAYNPLYTNQYSQGAAAVGTAGAILAALPT 314
            :.|.:|:.|.|||..:.||...|.:|..:..|       |:|                   .:|
Zfish   260 ELLHLTLEIVEKRNTVPDFGSEVMAEALAMAK-------PVY-------------------KIP- 297

  Fly   315 GLLPGGAGAAGNANVFGSASQYLNSSNLTMDAISGSGNGNSSRKEKRPYKKRKHKLPRDKQQHQQ 379
             ::|           |.:::||.:..::..             ||.:. |..|.::.|.|::::
Zfish   298 -IIP-----------FSNSTQYRHQDHIDF-------------KEYKT-KPEKPEVVRTKRKYE- 335

  Fly   380 QQTQQHQQQQYLPASGGAGVSPAHHLPHHLHHLSRQQSASPAANDSIADSEEEDYFGAGAQNGNK 444
                  ::.:.||.|     :|.|..|...:.....|...|:::|     |......:|:
Zfish   336 ------KKPKLLPLS-----APLHTGPSLFNPKDLNQYDFPSSDD-----EPFSQIHSGS----- 379

  Fly   445 LGSESEEET----PFAFRRRSSCVYLPTR-QRDGRYPWDSADEDMAPSGACSDAKYRYTLTSLNY 504
              ||:|||.    .|||||::.|||...| .:.|.:|| |.:.|    |...:.::||:||:|..
Zfish   380 --SEAEEENEPDGAFAFRRKAGCVYHAARLDQSGDWPW-SGEAD----GRSCNPRFRYSLTTLTI 437

  Fly   505 PRPRCIGFARRRLGRGGRILLDRATTNFDDFWSQLDYTVMESVTVNKCRDKIKQRDPDQLCKPSS 569
            || ||:|.||||:|||||..||||.::.:..:..||                ...:|| ...|:|
Zfish   438 PR-RCVGLARRRVGRGGRFHLDRAYSDLNGLFQSLD----------------TDSEPD-FSFPAS 484

  Fly   570 PPTVVDLVPAGKPVDGEHPVPELIKEEPS----SDTEKPVAATES--GRESKERELEEKFENDVD 628
            |   :......:.|...|....|.....|    ||..:.:.:..|  .|..|.|.|..  ::...
Zfish   485 P---LHTESTSQSVTSTHTSSTLQTSSSSHTAYSDLRQVLRSIRSCRWRHFKPRTLTS--QSGTG 544

  Fly   629 DEFVASDDENVSRLGIYSSAVTL-------PQSCA----DLRQKRRRLR-RKKQQLRELNAAKRL 681
            |.......:.:.|.|......|:       |.:.|    ..:|.:.:|. .:||||.::......
Zfish   545 DAPTRRAIKGLIRGGAGPGGSTMGRTAGMGPPAVAFTAEQYQQHQEQLALMQKQQLEQIQHQANN 609

  Fly   682 KRSSEAVA--TAEDVQLEDEDTKPDLRPLPRAYLQRLALILGQK---LKVEED------------ 729
            ..||:::.  |.:.|.               |.....||:...:   |||:||
Zfish   610 SASSQSLVSKTLDSVS---------------AQFAASALMTSDQLLTLKVKEDGAGGGVNGVIQA 659

  Fly   730 ----DNTEVSENVAPELLEMNDPEQLQPPRANHQQHHRSNHNNNN-------NTVLNNNNSSSSN 783
                ....:|...:..|:.........||.      ..|:.:|:|       :|.:.|:.:|::|
Zfish   660 SGVYKGLSISSTSSSALITSQSAPTAAPPT------FLSSSSNSNTSSTHSVHTPIGNHGNSTAN 718

  Fly   784 VMNKDVSISEKINVIKQEAEELVGGKCEDQPVASTSAAAAAARAAEAA------AAAEAASSTTT 842
                            ..::.|:|.... ..|.:.|.|:..||....:      ||.:.|:|...
Zfish   719 ----------------SASQVLIGNNLR-LSVTAPSIASLNARHLPRSLSNVPPAALKLAASNCQ 766

  Fly   843 LAAPNPGPSLEEVAKTI 859
            |...|.|...|:..:::
Zfish   767 LPKANAGEKHEQEKQSL 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(Pc)	NP_001260897.1	EPL1	7..139	CDD:287484	75/141 (53%)
epc1a	XP_695062.2	EPL1	7..148	CDD:287484	75/141 (53%)
		E_Pc_C	579..796	CDD:284226	45/243 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592428
Domainoid	1	1.000	160	1.000	Domainoid score	I4017
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	419	1.000	Inparanoid score	I1778
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001287
OrthoInspector	1	1.000	-	-		otm24238
orthoMCL	1	0.900	-	-		OOG6_102490
Panther	1	1.100	-	-	O	PTHR14898
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1679
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.890