Protein Alignment E(Pc) and Epc1

DIOPT Version :9

• Sequence 1: NP_001260897.1
• Gene: E(Pc) / 36238
• FlyBaseID: FBgn0000581
• Length: 2097
• Species: Drosophila melanogaster
• Sequence 2: XP_038951208.1
• Gene: Epc1 / 100362678
• RGDID: 2324280
• Length: 816
• Species: Rattus norvegicus
• Alignment Length: 976
• Identity: 316/976 - (32%)
• Similarity: 465/976 - (47%)
• Gaps: 260/976 - (26%)

  Fly     1 MSKLSFRARHLDPSKQMPIYLAEELPDLPEYSAINRAVPQMPSGMEKEEESEHHLQRAICT---- 61
            |||||||||.||.||.:|::..|:||||.||::|||||||||:||||||||||||||||..
  Rat     1 MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVY 65

  Fly    62 -----GLIIPTPEVLQTDQPFYDAYYPPDYKMPRQMIHMQPLGLDTEVPDYDMDSADEDWLSQ-Q 120
                 .::||.||. :::..:|::.||.::|||:|:||:||..||.|.||||:||.||.:::: :
  Rat    66 GEKRDNMVIPVPEA-ESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLK 129

  Fly   121 QRLELTELKFEQMMDRLEKSSGQTV----VTLNEAKSLLNQDDETSISVYDYWLNKRLKMQHP-L 180
            :::::..::||:|:|||||.|||.|    |:|.|||.||.:|||....||:||:.||...:.| |
  Rat   130 KKMDICPVQFEEMIDRLEKGSGQQVQLHPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGPSL 194

  Fly   181 ILTVKTESRPGASSNNPYLAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLQRATTILEMVRRRE 245
            |.:||.|.|.|:|:|:||:||||||||||||||||||||||||||||||||.||.|||||::|||
  Rat   195 IPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRRE 259

  Fly   246 ETKRDHLKMTVNIFEKRVEMRDFNGAVYSELNSQYKNTRPAYNPLYTNQYSQGAAAVGTAGAILA 310
            ::||:.|.:|:.|.|||..:.|::|.:.||:.:|.:..:|.|
  Rat   260 KSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTY----------------------- 301

  Fly   311 ALPTGLLPGGAGAAGNANVFGSASQYLNSSNLTMDAISGSGNGNSSRKEKRPYKKRKHKLPRDKQ 375
            |:|  ::|                 ..|||......::.:       ||.:..|:.|..|.|.|:
  Rat   302 AIP--IIP-----------------ITNSSQFKHQDVTDA-------KEFKVNKQDKADLIRPKR 340

  Fly   376 QHQQQQTQQHQQQQYLPASGGAGVSPAHHLPHHLHHLSRQQSASPAA--NDSIADSEEEDYFGAG 438
            :::       ::.:.||:|..|                 .|..||||  ..|..|..:.|:..:.
  Rat   341 KYE-------KKPKVLPSSAAA-----------------PQQPSPAALPGFSAKDLNQYDFPSSD 381

  Fly   439 AQNGNKL---GSESEEET----PFAFRRRSSC-VYLPTRQRDGRYPWDSADEDMAPSGACSDAKY 495
            .:..:::   .||:|||.    ||||||::.| .|.|...:.|.:||.|..:     |...|.:|
  Rat   382 EEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRY 441

  Fly   496 RYTLTSLNYPRPRCIGFARRRLGRGGRILLDRATTNFDDFWSQLDYTVMES---VTVNKCRDKIK 557
            ||.||:|..|: ||:||||||:|||||:|||||.:::|..:..||..::.|   ..||:..:..:
  Rat   442 RYCLTTLTVPQ-RCLGFARRRVGRGGRVLLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSE 505

  Fly   558 QRDPDQLCKPSS---PPTVVDLVPAGKPVDGEH---PVPELIKEEPSSDTEKPVAATESGRESKE 616
            ....|   :|||   ...:||:    |.....|   ..|.|    |.||         || |...
  Rat   506 TNTSD---RPSSKDLSQILVDI----KSCRWRHFRPRTPSL----PDSD---------SG-ELSS 549

  Fly   617 RELEEKFENDVDDEFVASDDENVSRLGIYSSAVTLPQSCADLRQKRRRLRRKKQQLRELNAAKRL 681
            |:|.                .::||.|   .|.....:|:...|.|..
  Rat   550 RKLH----------------RSISRAG---PAQPGAHTCSASTQSRSS----------------- 578

  Fly   682 KRSSEAVATAEDVQLEDEDTKPDLRPLPRAYLQRLALILGQKL-KVEEDDNTEVSENVAPELLEM 745
            ..|:....|||..|               .:.|:|||:..|:| :.::......|...||:
  Rat   579 SGSTHCAFTAEQYQ---------------QHQQQLALMQQQQLAQTQQQQANSSSSTAAPQ---- 624

  Fly   746 NDPEQLQPPRANHQQHHRSNHNNNNNTVLNNNNSSSSNVMNKDVSISEKINVIKQEAEELVG--- 807
                                     ..|....:|:|:......:..||::...|.:.:.::|
  Rat   625 -------------------------GFVSKTLDSASAQFAASALMTSEQLMGFKMKDDVVLGIGV 664

  Fly   808 -------GKCEDQPVASTSAAAAAARAAEAAAA---------------------AEAASSTTT-- 842
                   |..:...::||:..|....:...|.:                     ..||:|.||
  Rat   665 NGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSALSHQVTAANSATTQV 729

  Fly   843 -------LAAPNPGPSLEEVAKTIKREMIDADDSNEPLSSIRTAAVMLSTQTSVSELMDDEAEDD 900
                   |..|:..|::..:| .|....|....|..|.|:::.||   :....||::....:.|.
  Rat   730 LFGNNIRLTVPSSVPTVNSIA-PINARHIPRTLSAVPPSALKLAA---AANCQVSKVPSSSSVDS 790

  Fly   901 V 901
            |
  Rat   791 V 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(Pc)	NP_001260897.1	EPL1	7..139	CDD:287484	72/141 (51%)
Epc1	XP_038951208.1	EPL1	7..148	CDD:402235	72/141 (51%)
		E_Pc_C	615..816	CDD:399616	35/210 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350709
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2261
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001287
OrthoInspector	1	1.000	-	-		otm45731
orthoMCL	1	0.900	-	-		OOG6_102490
Panther	1	1.100	-	-	LDO	PTHR14898
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1679
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790