Protein Alignment Prip and AQP10

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: XP_011508406.1
• Gene: AQP10 / 89872
• HGNCID: 16029
• Length: 302
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 73/281 - (25%)
• Similarity: 114/281 - (40%)
• Gaps: 61/281 - (21%)

  Fly    10 LNELKSKELRLWQALIGEFLGNLIL-NFFACGACTQ-IEDGTFKA------LAFGLAIFMAITIV 66
            :..|:.:.|...|.| .||||..:| .....||..| :..|..|.      ||..||:.:||.:.
Human    11 MGHLRIRSLLARQCL-AEFLGVFVLMQLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVG 74

  Fly    67 GHLSGGHVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILID---QDYYNG------ 122
            |::||.|:|||.:..|.:.||:..::...|::.|.|.|...:.|..:|..   |:|..|
Human    75 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTG 139

  Fly   123 ------LGHTSLAPNIT-------ELQGLGIEFFLGLLLVLVVFGACDPHKPDSRYTA------P 168
                  :..|..||.::       ::.|.|: ..:|||.:|           |.|...      |
Human   140 PKETASIFATYPAPYLSLNNGFLDQVLGTGM-LIVGLLAIL-----------DRRNKGVPAGLEP 192

  Fly   169 LAIGMAVTLGHLGTIRYTGASMNPARTVGTAFATDI--WASH---------WVYWVGPVLGGVAA 222
            :.:||.:....|......|..:||||.:|....|.:  |...         ||..|.|::|....
Human   193 VVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVG 257

  Fly   223 ALLYTQVLEAKPVPKVNEASE 243
            ...| |:|.|...|:..|.::
Human   258 TATY-QLLVALHHPEGPEPAQ 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	67/260 (26%)
AQP10	XP_011508406.1	MIP	13..266	CDD:444743	70/266 (26%)