DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prip and AQY1

DIOPT Version :9

Sequence 1:	NP_001246266.1	Gene:	Prip / 36237	FlyBaseID:	FBgn0033635	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_015518.1	Gene:	AQY1 / 856322	SGDID:	S000006396	Length:	305	Species:	Saccharomyces cerevisiae

Alignment Length:	249	Identity:	67/249 - (26%)
Similarity:	112/249 - (44%)	Gaps:	34/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ALIGEFLGNLILNFFACG-----------ACTQIEDGTFK------ALAFGLAIFMAITIVGHLS 70
            |.:|||.|..:  |..|.           |.....||:..      |:.||.::..:|.....:|
Yeast    51 AAVGEFCGTFM--FLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVS 113

  Fly    71 GGHVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITEL 135
            ||.:|||::..:.:|..:|..|.....|.|.:..:|...|...:...:.   |...||....:..
Yeast   114 GGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEV---LFANSLGLGCSRT 175

  Fly   136 QGLGIEFF-LGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTA 199
            :||.:|.| ..:|.:.|:..|.:  |.::.:.|.|.||:::.:.|:....|||..:||||::|.|
Yeast   176 RGLFLEMFGTAILCLTVLMTAVE--KRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAA 238

  Fly   200 FATDIWAS-HWVYWVGPVLGGVAA--------ALLYTQVLEAKPVPKVNEASEK 244
            .|...:.. ||:||:|.:||.:.|        .|.||..:.|:......|.::|
Yeast   239 VAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	62/229 (27%)
AQY1	NP_015518.1	MIP	54..266	CDD:273306	60/218 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I1786
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1546
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		mtm9195
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
TreeFam	1	0.960	-	-
	10	9.750