DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prip and aqp8a.1

DIOPT Version :9

Sequence 1:	NP_001246266.1	Gene:	Prip / 36237	FlyBaseID:	FBgn0033635	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001004661.1	Gene:	aqp8a.1 / 447923	ZFINID:	ZDB-GENE-040912-106	Length:	260	Species:	Danio rerio

Alignment Length:	227	Identity:	74/227 - (32%)
Similarity:	106/227 - (46%)	Gaps:	21/227 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QALIGEFLGNLILNFFAC-------GACTQIEDGTFKALAFGLAIFMAITIVGHLSGGHVNPAVT 79
            |..:.|.:|:.:..|..|       |....|:    .|||.|||:.:||.|.|.:||||.||||:
Zfish    37 QPCLAEVVGSFLFMFVGCVSVMGNVGISGSIQ----PALAHGLALAIAIAIFGEISGGHFNPAVS 97

  Fly    80 AGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPN-ITELQGLG---- 139
            ..:.:.|.:.:|....|::.|.||.:...:..|.:...|.::..  |..|.| |....|:|
Zfish    98 VCVYLIGGMEVILLVPYIISQMLGGVIAASLAKAVTTNDAFSNA--TGAAFNAIPSSDGIGAATM 160

  Fly   140 IEFFLGLLLVLVV-FGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFATD 203
            .|..:.|.|.:|| .||.:......  .||..||:.||...|.....:||.|||||..|.|..:.
Zfish   161 AEMIMTLFLTIVVSMGAVNGRTKSQ--LAPFCIGLTVTANILAGGGISGACMNPARAFGPAVVSG 223

  Fly   204 IWASHWVYWVGPVLGGVAAALLYTQVLEAKPV 235
            .|..||:|||||:.|.:....:...|:..|.|
Zfish   224 HWTHHWIYWVGPLTGALVTVSIVRLVMGDKKV 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	71/216 (33%)
aqp8a.1	NP_001004661.1	MIP	39..249	CDD:294134	70/217 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760