Protein Alignment Prip and MIP

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_036196.1
• Gene: MIP / 4284
• HGNCID: 7103
• Length: 263
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 95/251 - (37%)
• Similarity: 134/251 - (53%)
• Gaps: 14/251 - (5%)

  Fly    12 ELKSKELRLWQALIGEFLGNLILNFFACGACTQIEDGTFK----ALAFGLAIFMAITIVGHLSGG 72
            ||:|..  .|:|:..||...|...||..|:..:...|...    |:|||||:...:..|||:||.
Human     3 ELRSAS--FWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAMAFGLALATLVQSVGHISGA 65

  Fly    73 HVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQG 137
            |||||||...||..::||:|||.|:..|.|||:||.|.:..:........|...:|.|.::..|.
Human    66 HVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHPAVSVGQA 130

  Fly   138 LGIEFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFAT 202
            ..:|.||.|..||.:|...|..:.....:..||:|.::.||||..:.||||.|||||:...|..|
Human   131 TTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILT 195

  Fly   203 DIWASHWVYWVGPVLGGVAAALLYTQVLEAKPVPKVNEASEKYRTHADEREGCKPN 258
            ..:.:||||||||::||...:|||..:|    .|::...||:...    .:|.||:
Human   196 GNFTNHWVYWVGPIIGGGLGSLLYDFLL----FPRLKSISERLSV----LKGAKPD 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	86/217 (40%)
MIP	NP_036196.1	MIP	3..219	CDD:395174	86/217 (40%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P06624	68..70		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P06624	184..186		1/1 (100%)
		Interaction with CALM. /evidence=ECO:0000250|UniProtKB:P06624	227..237		2/13 (15%)