Protein Alignment Prip and AQP7

DIOPT Version :9

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001161.1
• Gene: AQP7 / 364
• HGNCID: 640
• Length: 342
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 65/270 - (24%)
• Similarity: 108/270 - (40%)
• Gaps: 45/270 - (16%)

  Fly    19 RLWQALIGEFLGNLILNFFACGACTQI----EDGTFKA--LAFGLAIFMAITIVGHLSGGHVNPA 77
            ::.:..:.||:...::..|..|:...:    :.|::..  |.||..:.|.:.:.|.:||.|:|.|
Human    32 KMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAA 96

  Fly    78 VTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGH----------------- 125
            ||......||:...:...||:.|.||:....|.:..|    :|..:.|
Human    97 VTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSL----FYTAILHFSGGQLMVTGPVATAGI 157

  Fly   126 --TSLAPNITELQGLGIEFFLGLLLVLVVFGACD-PHKPDSRYTAPLAIGMAVTLGHLGTIRYTG 187
              |.|..::|..:|...|.:|..:|.|.:|...| .:.|....|..|.||:.|.:..:.....||
Human   158 FATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTG 222

  Fly   188 ASMNPARTVGTAFATDI--WASH---------WVYWVGPVLGGVAAALLYTQVLEAKPVPKVN-- 239
            .::||:|.:.....|.|  |...         ||..|.|:||.....::|. |.....:|:..
Human   223 YAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYL-VFIGSTIPREPLK 286

  Fly   240 -EASEKYRTH 248
             |.|..|..|
Human   287 LEDSVAYEDH 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	58/243 (24%)
AQP7	NP_001161.1	MIP	31..280	CDD:412216	60/252 (24%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P55064	94..96		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P55064	226..228		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850