Protein Alignment Prip and AQP1

DIOPT Version :9

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001316801.1
• Gene: AQP1 / 358
• HGNCID: 633
• Length: 323
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 100/263 - (38%)
• Similarity: 145/263 - (55%)
• Gaps: 28/263 - (10%)

  Fly    11 NELKSKELRLWQALIGEFLGNLILNFFACGAC-----------TQIEDGTFKALAFGLAIFMAIT 64
            :|.|.|  ..|:|::.|||...:..|.:.|:.           |.::|....:|||||:|.....
Human     3 SEFKKK--LFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQ 65

  Fly    65 IVGHLSGGHVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLA 129
            .|||:||.|:|||||.|:|::.:||:.||..|::.||:|||..||.:..:......|.||...||
Human    66 SVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLA 130

  Fly   130 PNITELQGLGIEFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPAR 194
            ..:...||||||....|.|||.|....|..:.|...:||||||::|.||||..|.|||..:||||
Human   131 DGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPAR 195

  Fly   195 TVGTAFATDIWASHWVYWVGPVLGGVAAALLYTQVLEAKPVPKVNEAS-----------EKYRTH 248
            :.|:|..|..:::||::||||.:||..|.|:|..:|    .|:.::.:           |:|...
Human   196 SFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFIL----APRSSDLTDRVKVWTSGQVEEYDLD 256

  Fly   249 ADE 251
            ||:
Human   257 ADD 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	93/224 (42%)
AQP1	NP_001316801.1	NPA 1	76..78		1/1 (100%)
		NPA 2	192..194		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68051
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.860