Protein Alignment Prip and Aqp8

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_062031.1
• Gene: Aqp8 / 29172
• RGDID: 2146
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 239
• Identity: 77/239 - (32%)
• Similarity: 116/239 - (48%)
• Gaps: 22/239 - (9%)

  Fly     7 SLGLNELKSKELRL--------W-----QALIGEFLGNLILNFFACGACTQIEDGT---FKALAF 55
            |:.|.|:|.||..:        |     |..:.|.||:.:..|..|.:..:....|   ..|||.
  Rat    10 SMDLREIKGKETNMADSYHGMSWYEQYIQPCVVELLGSALFIFIGCLSVIENSPNTGLLQPALAH 74

  Fly    56 GLAIFMAITIVGHLSGGHVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQD-Y 119
            |||:.:.|..:|::||||.||||:..:.:.|.:..:....|.|.|..|.:.|.|..|::..:: :
  Rat    75 GLALGLIIATLGNISGGHFNPAVSLAVTLVGGLKTMLLIPYWVSQLFGGMIGAALAKVVSPEERF 139

  Fly   120 YNGLGHTSLAPNITE--LQGLGIEFFLGLLLVLVV-FGACDPHKPDSRYTAPLAIGMAVTLGHLG 181
            :|..|.........|  .:.||:|..:.:||||.| .||.  ::......||.:||.:|.:..|.
  Rat   140 WNASGAAFAIVQEQEQVAEALGVEIVMTMLLVLAVCMGAV--NEKTMGPLAPFSIGFSVIVDILA 202

  Fly   182 TIRYTGASMNPARTVGTAFATDIWASHWVYWVGPVLGGVAAALL 225
            ....:||.|||||..|.|.....|..||:||:||:|.|:...||
  Rat   203 GGGISGACMNPARAFGPAVMAGYWDFHWIYWLGPLLAGLFVGLL 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	75/234 (32%)
Aqp8	NP_062031.1	MIP	40..250	CDD:444743	69/209 (33%)
		NPA 1	94..96		1/1 (100%)
		NPA 2	212..214		1/1 (100%)