DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prip and Aqp6

DIOPT Version :9

Sequence 1:	NP_001246266.1	Gene:	Prip / 36237	FlyBaseID:	FBgn0033635	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_071517.1	Gene:	Aqp6 / 29170	RGDID:	71100	Length:	276	Species:	Rattus norvegicus

Alignment Length:	228	Identity:	86/228 - (37%)
Similarity:	112/228 - (49%)	Gaps:	28/228 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LW----QALIGEFLGNLILNFFACG----------ACTQIEDGTFKALAFGLAIFMAITIVGHLS 70
            ||    :||..|||...:..||..|          :..|:      |:.|.||...|:.|....|
  Rat    16 LWTAISKALFAEFLATGLYVFFGVGSVLPWPVALPSVLQV------AITFNLATATAVQISWKTS 74

  Fly    71 GGHVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITEL 135
            |.|.|||||...||...|||.||..|:..|..||..|.|.:..:........||...:..:.:..
  Rat    75 GAHANPAVTLAYLVGSHISLPRAVAYIAAQLAGATVGAALLYGVTPGGVRETLGVNVVHNSTSTG 139

  Fly   136 QGLGIEFFLGLLLVLVVFGACDPHKPDSRYT--APLA-IGMAVTLGHLGTIRYTGASMNPARTVG 197
            |.:.:|..|.|.|||.||.:.     |||.|  :|.| ||.:|.||||..|.:||.||||||:.|
  Rat   140 QAVAVELVLTLQLVLCVFASM-----DSRQTLGSPAAMIGTSVALGHLIGIYFTGCSMNPARSFG 199

  Fly   198 TAFATDIWASHWVYWVGPVLGGVAAALLYTQVL 230
            .|.....:|.||::||||:.|.|.|:|:|..:|
  Rat   200 PAVIVGKFAVHWIFWVGPLTGAVLASLIYNFIL 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	84/222 (38%)
Aqp6	NP_071517.1	MIP	22..228	CDD:294134	82/216 (38%)
		NPA 1	79..81		1/1 (100%)
		NPA 2	193..195		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.030