DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prip and Mip

DIOPT Version :9

Sequence 1:	NP_001246266.1	Gene:	Prip / 36237	FlyBaseID:	FBgn0033635	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001099189.1	Gene:	Mip / 25480	RGDID:	3090	Length:	263	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	95/251 - (37%)
Similarity:	135/251 - (53%)	Gaps:	14/251 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ELKSKELRLWQALIGEFLGNLILNFFACGACTQIEDGTFK----ALAFGLAIFMAITIVGHLSGG 72
            ||:|..  .|:|:..||...|...||..|:..:...|...    |||||||:...:..|||:||.
  Rat     3 ELRSAS--FWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVALAFGLALATLVQTVGHISGA 65

  Fly    73 HVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQG 137
            |||||||...||..::||:|||.|:..|.|||:||.|.:..:........|...:|...::..|.
  Rat    66 HVNPAVTFAFLVGSQMSLLRAFCYIAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHAGVSVGQA 130

  Fly   138 LGIEFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFAT 202
            ..:|.||.|..||.:|...|..:.....:..||:|.::|||||..:.||||.|||||:...|..|
  Rat   131 TTVEIFLTLQFVLCIFATYDERRNGRMGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILT 195

  Fly   203 DIWASHWVYWVGPVLGGVAAALLYTQVLEAKPVPKVNEASEKYRTHADEREGCKPN 258
            ..:::||||||||::||...:|||..:|    .|::...||:...    .:|.:|:
  Rat   196 RNFSNHWVYWVGPIIGGGLGSLLYDFLL----FPRLKSVSERLSI----LKGARPS 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	87/217 (40%)
Mip	NP_001099189.1	MIP	3..219	CDD:278651	87/217 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930