Protein Alignment Prip and Mip

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001099189.1
• Gene: Mip / 25480
• RGDID: 3090
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 251
• Identity: 95/251 - (37%)
• Similarity: 135/251 - (53%)
• Gaps: 14/251 - (5%)

  Fly    12 ELKSKELRLWQALIGEFLGNLILNFFACGACTQIEDGTFK----ALAFGLAIFMAITIVGHLSGG 72
            ||:|..  .|:|:..||...|...||..|:..:...|...    |||||||:...:..|||:||.
  Rat     3 ELRSAS--FWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVALAFGLALATLVQTVGHISGA 65

  Fly    73 HVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQG 137
            |||||||...||..::||:|||.|:..|.|||:||.|.:..:........|...:|...::..|.
  Rat    66 HVNPAVTFAFLVGSQMSLLRAFCYIAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHAGVSVGQA 130

  Fly   138 LGIEFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFAT 202
            ..:|.||.|..||.:|...|..:.....:..||:|.::|||||..:.||||.|||||:...|..|
  Rat   131 TTVEIFLTLQFVLCIFATYDERRNGRMGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILT 195

  Fly   203 DIWASHWVYWVGPVLGGVAAALLYTQVLEAKPVPKVNEASEKYRTHADEREGCKPN 258
            ..:::||||||||::||...:|||..:|    .|::...||:...    .:|.:|:
  Rat   196 RNFSNHWVYWVGPIIGGGLGSLLYDFLL----FPRLKSVSERLSI----LKGARPS 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	87/217 (40%)
Mip	NP_001099189.1	MIP	3..219	CDD:395174	87/217 (40%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P06624	68..70		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P06624	184..186		1/1 (100%)
		Interaction with CALM. /evidence=ECO:0000250|UniProtKB:P06624	227..237		2/13 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..263		1/4 (25%)