Protein Alignment Prip and Aqp2

DIOPT Version :9

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_037041.3
• Gene: Aqp2 / 25386
• RGDID: 2142
• Length: 271
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 97/269 - (36%)
• Similarity: 141/269 - (52%)
• Gaps: 22/269 - (8%)

  Fly    12 ELKSKELRLWQALIGEFLGNLILNFFACGACTQIEDGTFK----ALAFGLAIFMAITIVGHLSGG 72
            ||:|  :...:|::.|||..|:..||..|:..|.......    |:||||.|...:..:||:||.
  Rat     3 ELRS--IAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGTLVQALGHVSGA 65

  Fly    73 HVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQG 137
            |:|||||...||...:|.:||.|||..|.|||:||.|.:..:...:....|...:|..|.|..|.
  Rat    66 HINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQA 130

  Fly   138 LGIEFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFAT 202
            :.:|.||.:.|||.:|.:.|..:.|:..:..|:||.:||||||..|.:||.||||||::..|..|
  Rat   131 VTVELFLTMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVT 195

  Fly   203 DIWASHWVYWVGPVLGGVAAALLYTQVLEAKPVPKVNEASEKYR--------THADEREGCKPN- 258
            ..:..|||:|:||::|.:..:|||..:|    .|......|:..        |..:|||..:..
  Rat   196 GKFDDHWVFWIGPLVGAIIGSLLYNYLL----FPSAKSLQERLAVLKGLEPDTDWEEREVRRRQS 256

  Fly   259 ---HNPNHL 264
               |:|..|
  Rat   257 VELHSPQSL 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	85/217 (39%)
Aqp2	NP_037041.3	MIP	3..219	CDD:395174	85/217 (39%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P41181	68..70		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P41181	184..186		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	251..271		3/15 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930