DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prip and Aqp5

DIOPT Version :9

Sequence 1:NP_001246266.1 Gene:Prip / 36237 FlyBaseID:FBgn0033635 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_036911.1 Gene:Aqp5 / 25241 RGDID:2144 Length:265 Species:Rattus norvegicus


Alignment Length:261 Identity:97/261 - (37%)
Similarity:138/261 - (52%) Gaps:36/261 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 LRLWQALIGEFLGNLILNFFACGAC----------TQIEDGTFKALAFGLAIFMAITIVGHLSGG 72
            |..::|:..|||..||..||..|:.          .||      ::||||||......:|.:|||
  Rat     8 LAFFKAVFAEFLATLIFVFFGLGSALKWPSALPTILQI------SIAFGLAIGTLAQALGPVSGG 66

  Fly    73 HVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQG 137
            |:|||:|..:|:..:|||:||.|||..|.:|||||...:..|...:....|...:|..|.|..:.
  Rat    67 HINPAITLALLIGNQISLLRAVFYVAAQLVGAIAGAGILYWLAPLNARGNLAVNALNNNTTPGKA 131

  Fly   138 LGIEFFLGLLLVLVVFGACDPHKPDSRYTAP-----LAIGMAVTLGHLGTIRYTGASMNPARTVG 197
            :.:|..|...|.|.:|.:     .|||.|:|     |:||::||||||..|.:||.||||||:.|
  Rat   132 MVVELILTFQLALCIFSS-----TDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFG 191

  Fly   198 TAFATDIWA-SHWVYWVGPVLGGVAAALLYTQVL---------EAKPVPKVNEASEKYRTHADER 252
            .|...:.:: ||||:||||::|.:.||:||..:|         ....|....|..|.:..|.:||
  Rat   192 PAVVMNRFSPSHWVFWVGPIVGAMLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEEDWEDHREER 256

  Fly   253 E 253
            :
  Rat   257 K 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PripNP_001246266.1 MIP 12..226 CDD:294134 88/223 (39%)
Aqp5NP_036911.1 MIP 4..221 CDD:395174 88/223 (39%)
NPA 1. /evidence=ECO:0000250|UniProtKB:P55064 69..71 1/1 (100%)
NPA 2. /evidence=ECO:0000250|UniProtKB:P55064 185..187 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53729
OrthoDB 1 1.010 - - D1152704at2759
OrthoFinder 1 1.000 - - FOG0000054
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19139
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X83
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
77.030

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