Protein Alignment Prip and Aqp8

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_031500.1
• Gene: Aqp8 / 11833
• MGIID: 1195271
• Length: 261
• Species: Mus musculus
• Alignment Length: 237
• Identity: 78/237 - (32%)
• Similarity: 114/237 - (48%)
• Gaps: 20/237 - (8%)

  Fly     7 SLGLNELKSKELR------LW-----QALIGEFLGNLILNFFACGACTQIEDGT---FKALAFGL 57
            |:.|.|:|.|...      .|     |..|.|.:|:.:..|..|.:..:....|   ..|||.||
Mouse    10 SMDLPEVKVKTSMAGRCRVFWYEQYVQPCIVELVGSALFIFIGCLSVIENSPNTGLLQPALAHGL 74

  Fly    58 AIFMAITIVGHLSGGHVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQD-YYN 121
            |:.:.|..:|::||||.||||:..:.|.|.:..:....|.:.|..|.:.|.|..|::..:: ::|
Mouse    75 ALGLIIATLGNISGGHFNPAVSLAVTVIGGLKTMLLIPYWISQLFGGLIGAALAKVVSPEERFWN 139

  Fly   122 GLGHTSLAPNITE--LQGLGIEFFLGLLLVLVV-FGACDPHKPDSRYTAPLAIGMAVTLGHLGTI 183
            ..|.........|  .:.||||..|.:||||.| .||.  ::......||.:||.:|.:..|...
Mouse   140 ASGAAFAIVQEQEQVAEALGIEIILTMLLVLAVCMGAV--NEKTMGPLAPFSIGFSVIVDILAGG 202

  Fly   184 RYTGASMNPARTVGTAFATDIWASHWVYWVGPVLGGVAAALL 225
            ..:||.|||||..|.|.....|..||:||:||:|.|:...||
Mouse   203 SISGACMNPARAFGPAVMAGYWDFHWIYWLGPLLAGLFVGLL 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	76/232 (33%)
Aqp8	NP_031500.1	MIP	38..248	CDD:444743	71/209 (34%)
		NPA 1	92..94		1/1 (100%)
		NPA 2	210..212		1/1 (100%)