Protein Alignment Prip and Aqp5

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_033831.1
• Gene: Aqp5 / 11830
• MGIID: 106215
• Length: 265
• Species: Mus musculus
• Alignment Length: 258
• Identity: 97/258 - (37%)
• Similarity: 138/258 - (53%)
• Gaps: 36/258 - (13%)

  Fly    21 WQALIGEFLGNLILNFFACGAC----------TQIEDGTFKALAFGLAIFMAITIVGHLSGGHVN 75
            ::|:..|||..||..||..|:.          .||      ::||||||......:|.:||||:|
Mouse    11 FKAVFAEFLATLIFVFFGLGSALKWPSALPTILQI------SIAFGLAIGTLAQALGPVSGGHIN 69

  Fly    76 PAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQGLGI 140
            ||:|..:|:..:|||:||.|||..|.:|||||...:..|...:....|...:|:.|.|..:.:.:
Mouse    70 PAITLALLIGNQISLLRAIFYVAAQLVGAIAGAGILYWLAPGNARGNLAVNALSNNTTPGKAVVV 134

  Fly   141 EFFLGLLLVLVVFGACDPHKPDSRYTAP-----LAIGMAVTLGHLGTIRYTGASMNPARTVGTAF 200
            |..|...|.|.:|.:     .|||.|:|     |:||::||||||..|.:||.||||||:.|.|.
Mouse   135 ELILTFQLALCIFSS-----TDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAV 194

  Fly   201 ATDIWA-SHWVYWVGPVLGGVAAALLYTQVL---------EAKPVPKVNEASEKYRTHADERE 253
            ..:.:: ||||:||||::|.|.||:||..:|         ....|....|..|.:..|.:||:
Mouse   195 VMNRFSPSHWVFWVGPIVGAVLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEEDWEDHREERK 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	88/220 (40%)
Aqp5	NP_033831.1	MIP	4..221	CDD:395174	88/220 (40%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P55064	69..71		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P55064	185..187		1/1 (100%)